Angiogenesis is an important step in tumor development and metastasis. Vascular
endothelial growth factor (VEGF) plays an important role in progression of angiogenesis …

Phage display is a powerful approach for evolving proteins and peptides with new functions,
but the properties of the molecules that can be evolved are limited by the chemical diversity …

One of the challenges of modern biotechnology is to find new routes to mitigate the
resistance to conventional antibiotics. Antimicrobial peptides (AMPs) are an alternative type …

Peptide-based vaccines have emerged in recent years as promising candidates in the
prevention of infectious diseases. However, there are many challenges to maintaining in …

Background The bovine ephemeral fever virus (BEFV) glycoprotein neutralization site 1
(also referred as G 1 protein), is a critical protein responsible for virus infectivity and eliciting …

The power of ribosomes has increasingly been harnessed for the synthesis and selection of
molecular libraries. Technologies, such as phage display, yeast display, and mRNA display …

In this report, we describe an efficient way to generate libraries of macrocyclic glycopeptides
in one step by reacting phage-displayed libraries of peptides with dichloro-oxime …

The isoelectric point (pI) is a fundamental physicochemical property of peptides and
proteins. It is widely used to steer design away from low solubility and aggregation and …

The field of regenerative medicine has been gaining momentum steadily over the past few
years. The emphasis in regenerative medicine is to use various in vitro and in vivo …

In recent years the ever so complex field of drug discovery has embraced novel design
strategies based on biophysical fragment screening (fragment-based drug design; FBDD) …