[HTML][HTML] Recent Advances Toward the Discovery of Drug-Like Peptides De novo

M Goldflam, CG Ullman - Frontiers in chemistry, 2015 - frontiersin.org
Peptides are important natural molecules that possess functions as diverse as antibiotics,
toxins, venoms and hormones, for example. However, whilst these peptides have useful …

[HTML][HTML] Characterization of a lytic Pseudomonas aeruginosa phage vB_PaeP_ASP23 and functional analysis of its lysin LysASP and holin HolASP

J Cui, X Shi, X Wang, H Sun, Y Yan, F Zhao… - Frontiers in …, 2023 - frontiersin.org
In this study, we isolated a lytic Pseudomonas aeruginosa phage (vB_PaeP_ASP23) from
the sewage of a mink farm, characterized its complete genome and analyzed the function of …

[HTML][HTML] Phage peptide libraries as a source of targeted ligands

AA Nemudraya, VA Richter… - Acta Naturae …, 2016 - cyberleninka.ru
One of the dominant trends in modern pharmacology is the creation of drugs that act directly
on the lesion focus and have minimal toxicity on healthy tissues and organs. This problem is …

Developing Lipase Inhibitor as a Novel Approach to Address the Rice Bran Rancidity Issue─ A Critical Review

Q Li, K Liu, G Cai, X Yang, JCK Ngo - Journal of Agricultural and …, 2024 - ACS Publications
Rice bran is a valuable byproduct from the food processing industry, which contains
abundant protein, essential unsaturated fatty acids, and numerous bioactive compounds …

Construction of an Immunized Rabbit Phage Display Library for Selecting High Activity against Bacillus thuringiensis Cry1F Toxin Single-Chain Antibodies

C Xu, C Zhang, J Zhong, H Hu, S Luo… - Journal of agricultural …, 2017 - ACS Publications
In the present study, a Cry1F-immunized rabbit phage display library (6.96× 108 cfu/mL) was
constructed for selecting high activity of anti-Cry1F toxin single-chain antibody (a single …

Peptide-activated gold nanoparticles for selective visual sensing of virus

B Sajjanar, B Kakodia, D Bisht, S Saxena… - Journal of Nanoparticle …, 2015 - Springer
In this study, we report peptide–gold nanoparticles (AuNP)-based visual sensor for viruses.
Citrate-stabilized AuNP (20±1.9 nm) were functionalized with strong sulfur–gold interface …

Endolysins: a new antimicrobial agent against antimicrobial resistance. Strategies and opportunities in overcoming the challenges of endolysins against Gram …

FM Khan, F Rasheed, Y Yang, B Liu… - Frontiers in …, 2024 - frontiersin.org
Antibiotic-resistant bacteria are rapidly emerging, and the increasing prevalence of
multidrug-resistant (MDR) Acinetobacter baumannii poses a severe threat to humans and …

[HTML][HTML] Bacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infection

B Bakhshinejad, M Sadeghizadeh - World Journal of …, 2014 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) infection is a major global health challenge leading to serious
disorders such as cirrhosis and hepatocellular carcinoma. Currently, there exist various …

Bacteriophages: cancer diagnosis, treatment, and future prospects

F Abbaszadeh, HE Leylabadlo, F Alinezhad… - Journal of …, 2021 - Springer
Background Early diagnosis is one of the most important factors in cancer treatment.
Unfortunately, despite remarkable advances in the diagnosis and treatment methods of …

Phage display as a tool to discover blood–brain barrier (BBB)‐shuttle peptides: panning against a human BBB cellular model

C Díaz‐Perlas, M Sánchez‐Navarro… - Peptide …, 2017 - Wiley Online Library
Most potential drugs for the treatment of central nervous system disorders do not cross the
blood–brain barrier (BBB). Much research effort has been devoted to the discovery of new …