Tumor cells do not exist in isolation in vivo, and carcinogenesis depends on the surrounding
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …

To flourish, cancers greatly depend on their surrounding tumor microenvironment (TME),
and cancer-associated fibroblasts (CAFs) in TME are critical for cancer occurrence and …

In recent years, breakthroughs have been made in tumor immunotherapy. However, tumor
immunotherapy, particularly anti-PD-1/PD-L1 immune checkpoint inhibitors, is effective in …

The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Purpose: The heterogeneity of high-grade serous ovarian cancer (HGSOC) is not well
studied, which severely hinders clinical treatment of HGSOC. Thus, it is necessary to …

Ovarian cancer is one of the leading causes of death in patients with gynecological
malignancy. Despite optimal cytoreductive surgery and platinum-based chemotherapy …

Purpose 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising
radiotracer for PET/CT imaging. The aim of this retrospective analysis is to explore the …

Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …

Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Cancer-associated fibroblasts (CAFs) are the key component of tumor stromal. High
heterogeneity of CAFs reflects in their origin, phenotype and function. Biological function …