Management of glioblastoma: State of the art and future directions

AC Tan, DM Ashley, GY López… - CA: a cancer journal …, 2020 - Wiley Online Library
Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …

Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Bevacizumab plus radiotherapy–temozolomide for newly diagnosed glioblastoma

OL Chinot, W Wick, W Mason… - … England Journal of …, 2014 - Mass Medical Soc
Background Standard therapy for newly diagnosed glioblastoma is radiotherapy plus
temozolomide. In this phase 3 study, we evaluated the effect of the addition of bevacizumab …

Standards of care for treatment of recurrent glioblastoma—are we there yet?

M Weller, T Cloughesy, JR Perry, W Wick - Neuro-oncology, 2013 - academic.oup.com
Newly diagnosed glioblastoma is now commonly treated with surgery, if feasible, or biopsy,
followed by radiation plus concomitant and adjuvant temozolomide. The treatment of …

Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent …

K Maier-Hauff, F Ulrich, D Nestler, H Niehoff… - Journal of neuro …, 2011 - Springer
Therapy options at the time of recurrence of glioblastoma multiforme are often limited. We
investigated whether treatment with a new intratumoral thermotherapy procedure using …

Radiation, inflammation and the immune response in cancer

KJ McKelvey, AL Hudson, M Back, T Eade… - Mammalian genome, 2018 - Springer
Radiation is an important component of cancer treatment with more than half of all patients
receive radiotherapy during their cancer experience. While the impact of radiation on tumour …

Radiation therapy for glioblastoma: executive summary of an American Society for Radiation Oncology evidence-based clinical practice guideline

AR Cabrera, JP Kirkpatrick, JB Fiveash, HA Shih… - Practical radiation …, 2016 - Elsevier
Purpose To present evidence-based guidelines for radiation therapy in treating glioblastoma
not arising from the brainstem. Methods and materials The American Society for Radiation …

Accelerator-based BNCT for patients with recurrent glioblastoma: a multicenter phase II study

S Kawabata, M Suzuki, K Hirose… - Neuro-oncology …, 2021 - academic.oup.com
Background Boron neutron capture therapy (BNCT) utilizes tumor-selective particle
radiation. This study aimed to assess the safety and efficacy of accelerator-based BNCT (AB …

[HTML][HTML] Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: a systematic review

SGC Kroeze, C Fritz, M Hoyer, SS Lo, U Ricardi… - Cancer treatment …, 2017 - Elsevier
Background and purpose Both stereotactic radiotherapy (SRT) and immune-or targeted
therapy play an increasingly important role in personalized treatment of metastatic disease …

Current status and recent advances in reirradiation of glioblastoma

G Minniti, M Niyazi, F Alongi, P Navarria, C Belka - Radiation Oncology, 2021 - Springer
Despite aggressive management consisting of maximal safe surgical resection followed by
external beam radiation therapy (60 Gy/30 fractions) with concomitant and adjuvant …