Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …
Prognostication after cardiac arrest
Hypoxic–ischaemic brain injury (HIBI) is the main cause of death in patients who are
comatose after resuscitation from cardiac arrest. A poor neurological outcome—defined as …
comatose after resuscitation from cardiac arrest. A poor neurological outcome—defined as …
Association of initial illness severity and outcomes after cardiac arrest with targeted temperature management at 36 C or 33 C
CW Callaway, PJ Coppler, J Faro, JS Puyana… - JAMA network …, 2020 - jamanetwork.com
Importance It is uncertain what the optimal target temperature is for targeted temperature
management (TTM) in patients who are comatose following cardiac arrest. Objective To …
management (TTM) in patients who are comatose following cardiac arrest. Objective To …
Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review
C Sandroni, S D'Arrigo, S Cacciola… - Intensive care …, 2022 - Springer
Purpose To assess the ability of clinical examination, blood biomarkers, electrophysiology or
neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to …
neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to …
Out-of-hospital cardiac arrest: in-hospital intervention strategies
C Hassager, K Nagao, D Hildick-Smith - The Lancet, 2018 - thelancet.com
The prognosis after out-of-hospital cardiac arrest (OHCA) has improved in the past few
decades because of advances in interventions used outside and in hospital. About half of …
decades because of advances in interventions used outside and in hospital. About half of …
Hypoxic-ischemic encephalopathy evaluated by brain autopsy and neuroprognostication after cardiac arrest
C Endisch, E Westhall, M Kenda, KJ Streitberger… - JAMA …, 2020 - jamanetwork.com
Importance Neuroprognostication studies are potentially susceptible to a self-fulfilling
prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining …
prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining …
Brain imaging in comatose survivors of cardiac arrest: pathophysiological correlates and prognostic properties
HM Keijzer, CWE Hoedemaekers, FJA Meijer… - Resuscitation, 2018 - Elsevier
Introduction Hypoxic-ischemic brain injury is the main cause of death and disability of
comatose patients after cardiac arrest. Early and reliable prognostication is challenging …
comatose patients after cardiac arrest. Early and reliable prognostication is challenging …
Neurophysiology and neuroimaging accurately predict poor neurological outcome within 24 hours after cardiac arrest: the ProNeCA prospective multicentre …
M Scarpino, F Lolli, G Lanzo, R Carrai, M Spalletti… - Resuscitation, 2019 - Elsevier
Aims To investigate the ability of 30-min electroencephalogram (EEG), short-latency
somatosensory evoked potentials (SEPs) and brain computed tomography (CT) to predict …
somatosensory evoked potentials (SEPs) and brain computed tomography (CT) to predict …
Awakening after cardiac arrest and post resuscitation hypothermia: are we pulling the plug too early?
B Gold, L Puertas, SP Davis, A Metzger… - Resuscitation, 2014 - Elsevier
Background Time to awakening after out-of-hospital cardiac arrest (OHCA) and post-
resuscitation therapeutic hypothermia (TH) varies widely. We examined the time interval …
resuscitation therapeutic hypothermia (TH) varies widely. We examined the time interval …
Protocol-driven neurological prognostication and withdrawal of life-sustaining therapy after cardiac arrest and targeted temperature management
I Dragancea, MP Wise, N Al-Subaie, J Cranshaw… - Resuscitation, 2017 - Elsevier
Background Brain injury is reportedly the main cause of death for patients resuscitated after
out-of-hospital cardiac arrest (OHCA). However, the majority may actually die following …
out-of-hospital cardiac arrest (OHCA). However, the majority may actually die following …