Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review
L Ghosn, R Assi, T Evrenoglou… - Cochrane database …, 2023 - cochranelibrary.com
Background It has been reported that people with COVID‐19 and pre‐existing
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …
Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection: from prognostic marker to therapeutic agent
J Declercq, E De Leeuw, BN Lambrecht - Cytokine, 2022 - Elsevier
Despite global vaccination programs, infections with severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) continue to cause severe disease with significant morbidity …
coronavirus-2 (SARS-CoV-2) continue to cause severe disease with significant morbidity …
[HTML][HTML] Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial
T Karampitsakos, O Papaioannou, P Tsiri… - Clinical Microbiology …, 2023 - Elsevier
Objective Randomized controlled trials comparing tocilizumab and baricitinib in patients with
coronavirus disease 2019 (COVID-19) are needed. This was an open-label, randomized …
coronavirus disease 2019 (COVID-19) are needed. This was an open-label, randomized …
[HTML][HTML] Characterisation of the pro-inflammatory cytokine signature in severe COVID-19
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …
[HTML][HTML] Liver injury in COVID-19: Clinical features, potential mechanisms, risk factors and clinical treatments
SW Zhao, YM Li, YL Li, C Su - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been a serious threat to
global health for nearly 3 years. In addition to pulmonary complications, liver injury is not …
global health for nearly 3 years. In addition to pulmonary complications, liver injury is not …
[HTML][HTML] Efficacy and safety of human umbilical cord-derived mesenchymal stem cells for COVID-19 pneumonia: a meta-analysis of randomized controlled trials
Q Liu, F Ma, Y Zhong, G Wang, L Hu, Y Zhang… - Stem Cell Research & …, 2023 - Springer
Background Elevated levels of inflammatory factors are associated with poor prognosis in
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …
[HTML][HTML] Association between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis
Background A recent prospective meta-analysis demonstrated that interleukin-6 antagonists
are associated with lower all-cause mortality in hospitalised patients with COVID-19 …
are associated with lower all-cause mortality in hospitalised patients with COVID-19 …
[HTML][HTML] Efficacy and safety of baricitinib and tocilizumab in hospitalized patients with COVID-19: a comparison using systematic review and meta-analysis
Objective: This review was performed to compare the efficacy and safety among hospitalized
patients with COVID-19 who received baricitinib and those who received tocilizumab …
patients with COVID-19 who received baricitinib and those who received tocilizumab …
Placebo effects on all‐cause mortality of patients with COVID‐19 in randomized controlled trials of interleukin 6 antagonists: A systematic review and network meta …
Aim Many randomized controlled trials (RCTs) have investigated the use of interleukin 6
antagonists for the treatment of coronavirus disease 2019 (COVID‐19), yielding inconsistent …
antagonists for the treatment of coronavirus disease 2019 (COVID‐19), yielding inconsistent …
Molecular mimicry, hyperactive immune system, and SARS-COV-2 are three prerequisites of the autoimmune disease triangle following COVID-19 infection
M Vahabi, T Ghazanfari, S Sepehrnia - International Immunopharmacology, 2022 - Elsevier
SARS-CoV-2 infection can produce a variety of clinical manifestations, which are either
directly related to viral tissue damage or indirectly induced by the antiviral immune …
directly related to viral tissue damage or indirectly induced by the antiviral immune …