Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by motor dysfunction. Growing evidence has demonstrated that gut dysbiosis …

Polyphenolic compounds (PC) are among the most abundant secondary metabolites in
nature. They are widely distributed in the world and can be found in fruits, cereals, tea …

Background The gut microbiota (GM) and brain are strongly associated, which significantly
affects neuronal development and disorders. GM-derived metabolites modulate neuronal …

The human gastrointestinal tract is home to a complex microbial community that plays an
important role in the general well-being of the entire organism. The gut microbiota generates …

The gastrointestinal tract is the main target of cadmium toxicity. However, whether
Akkermansia muciniphila (A. muciniphila), which has been reported to be the next …

Sleep deprivation has developed into a common phenomenon, which can lead to
inflammatory responses and cognitive impairment, but the underlying mechanism is …

Millions of nerves, immune factors, and hormones in the circulatory system connect the gut
and the brain. In bidirectional communication, the gut microbiota play a crucial role in the gut …

Background Simo decoction (SMD) is a traditional prescription for treating gastrointestinal
diseases. More and more evidences prove that SMD can treat constipation by regulating …

Ethnopharmacological relevance According to traditional Chinese medicine (TCM) theory,
post-traumatic stress disorder (PTSD) is a kind of depression syndrome, and its occurrence …

The microbiota-gut-brain axis is an important pathway of communication and may
dynamically contribute to Alzheimer's disease (AD) pathogenesis. Pathological commensal …