Articular cartilage serves as a low-friction, load-bearing tissue without the support with blood
vessels, lymphatics and nerves, making its repair a big challenge. Transforming growth …

The development of biomaterials, stem cells and bioactive factors has led to cartilage tissue
engineering becoming a promising tactic to repair cartilage defects. Various polymer three …

Degeneration of articular cartilage (AC) tissue is the most common cause of osteoarthritis
(OA) and rheumatoid arthritis. Bone morphogenetic proteins (BMPs) play important roles in …

Unregulated activity of myofibroblasts, highly contractile cells that deposit abundant
extracellular matrix (ECM), leads to fibrosis. To study the modulation of myofibroblast activity …

Recapitulating the microstructure of the native human corneal stromal tissue is believed to
be a key feature in successfully engineering the corneal tissue. The stratified multilayered …

The methods for cartilage repair have been studied so far, yet many of them seem to have
limitations due to the low regenerative capacity of articular cartilage. Mesenchymal stem cell …

Background Stem cell therapies represent a promising tool in regenerative medicine.
Considering the drawbacks of direct stem cell injections (eg poor cell localisation) …

Trauma, malposition and age‐related degeneration of articular cartilage often result in
severe lesions that do not heal spontaneously. Many efforts over the last centuries have …

The goal of tissue engineering is to create a functional replacement for tissues damaged by
injury or disease. In many cases, impaired tissues cannot provide viable cells, leading to the …

Fetal calf serum (FCS) bears a potential risk for carrying diseases and eliciting immune
reactions. Nevertheless, it still represents the gold standard as medium supplement in cell …