Orchestrating single-cell analysis with Bioconductor
Recent technological advancements have enabled the profiling of a large number of
genome-wide features in individual cells. However, single-cell data present unique …
genome-wide features in individual cells. However, single-cell data present unique …
Single-cell transcriptome analysis in plants: advances and challenges
The rapid and enthusiastic adoption of single-cell RNA sequencing (scRNA-seq) has
demonstrated that this technology is far more than just another way to perform transcriptome …
demonstrated that this technology is far more than just another way to perform transcriptome …
Democratising deep learning for microscopy with ZeroCostDL4Mic
Deep Learning (DL) methods are powerful analytical tools for microscopy and can
outperform conventional image processing pipelines. Despite the enthusiasm and …
outperform conventional image processing pipelines. Despite the enthusiasm and …
[HTML][HTML] Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19
Immune response dynamics in coronavirus disease 2019 (COVID-19) and their severe
manifestations have largely been studied in circulation. Here, we examined the relationship …
manifestations have largely been studied in circulation. Here, we examined the relationship …
Generalizing RNA velocity to transient cell states through dynamical modeling
RNA velocity has opened up new ways of studying cellular differentiation in single-cell RNA-
sequencing data. It describes the rate of gene expression change for an individual gene at a …
sequencing data. It describes the rate of gene expression change for an individual gene at a …
Does the human placenta express the canonical cell entry mediators for SARS-CoV-2?
The pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected more than 10 million …
Reconstructing aspects of human embryogenesis with pluripotent stem cells
B Sozen, V Jorgensen, BAT Weatherbee… - Nature …, 2021 - nature.com
Understanding human development is of fundamental biological and clinical importance.
Despite its significance, mechanisms behind human embryogenesis remain largely …
Despite its significance, mechanisms behind human embryogenesis remain largely …
Time-resolved single-cell RNA-seq using metabolic RNA labelling
Single-cell RNA genomics technologies are revolutionizing biomedical science by profiling
single cells with unprecedented resolution, providing fundamental insights into the role of …
single cells with unprecedented resolution, providing fundamental insights into the role of …
[HTML][HTML] Dermal adipocyte lipolysis and myofibroblast conversion are required for efficient skin repair
Mature adipocytes store fatty acids and are a common component of tissue stroma.
Adipocyte function in regulating bone marrow, skin, muscle, and mammary gland biology is …
Adipocyte function in regulating bone marrow, skin, muscle, and mammary gland biology is …
Solo: doublet identification in single-cell RNA-seq via semi-supervised deep learning
NJ Bernstein, NL Fong, I Lam, MA Roy… - Cell systems, 2020 - cell.com
Single-cell RNA sequencing (scRNA-seq) measurements of gene expression enable an
unprecedented high-resolution view into cellular state. However, current methods often …
unprecedented high-resolution view into cellular state. However, current methods often …