In developing a drug delivery strategy, issues of absorption, distribution, metabolism, and
elimination must be considered. The eye presents unique opportunities and challenges …

Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the
latest developments and challenges in carbonic anhydrase research. Authors describe the …

Horner's syndrome arises from dysfunction of the oculosympathetic pathway and is
characterized by miosis, enophthalmos, protrusion of the third eyelid, and ptosis. It has been …

IOP is the result of a delicate balance between production and outflow of aqueous humor
(Figure 12-3). In glaucoma both production and outflow are altered. Usually a large …

Objective To determine whether the combination multiple‐dose dorzolamide–timolol
administered topically has any greater effects on the reduction of intraocular pressure, pupil …

Objective—To determine effects after topical administration of latanoprost, timolol, or a
commercially available latanoprosttimolol combination twice daily on intraocular pressure …

The breakdown of blood-tear barrier that occurs with ocular pathology allows for large
amounts of albumin to leak into the tear fluid. This process likely represents an important …

Purpose To evaluate long‐term efficacy of antiglaucoma medications with or without
combined topical anti‐inflammatory treatment in preventing increased intraocular pressure …

Glaucoma is a diverse group of vision-impairing disorders that have as a common bond an
elevation of intraocular pressure (IOP) to a level incompatible with the health of the eye …

Glaucoma is a heterogeneous group of disorders usually associated with elevated
intraocular pressure (IOP), leading to optic nerve damage, retinal ganglion cell death and …