[HTML][HTML] Potential of cell-penetrating peptides (CPPs) in delivery of antiviral therapeutics and vaccines

I Sadeghian, R Heidari, S Sadeghian, MJ Raee… - European Journal of …, 2022 - Elsevier
Viral infections are a great threat to human health. Currently, there are no effective vaccines
and antiviral drugs against the majority of viral diseases, suggesting the need to develop …

[HTML][HTML] Targeting antigens for universal influenza vaccine development

QT Nguyen, YK Choi - Viruses, 2021 - mdpi.com
Traditional influenza vaccines generate strain-specific antibodies which cannot provide
protection against divergent influenza virus strains. Further, due to frequent antigenic shifts …

Monophosphoryl lipid A-adjuvanted nucleoprotein-neuraminidase nanoparticles improve immune protection against divergent influenza viruses

Y Wang, C Dong, Y Ma, W Zhu, HS Gill… - … , Biology and Medicine, 2023 - Elsevier
Universal influenza vaccines are urgently needed to prevent recurrent influenza epidemics
and inevitable pandemics. We generated double-layered protein nanoparticles …

Protein transduction domain of translationally controlled tumor protein: characterization and application in drug delivery

J Maeng, K Lee - Drug Delivery, 2022 - Taylor & Francis
Our research group reported in 2011 the discovery of a novel cell-penetrating moiety in the
N-terminus of the human translationally controlled tumor protein (TCTP). This moiety was …

Improving cross-protection against influenza virus in mice using a nanoparticle vaccine of mini-HA

H Zhu, X Li, X Ren, H Chen, P Qian - Vaccine, 2022 - Elsevier
This study aimed to investigate the protective effect of mini-hemagglutinin (mini-HA) proteins
expressed on lumazine synthase (LS) nanoparticles against influenza. Soluble mini-HA …

3-Fucosyllactose-Mediated Modulation of Immune Response against Virus Infection

S Moon, KW Lee, M Park, J Moon, SH Park… - International Journal of …, 2024 - Elsevier
3-Fucosyllactose-Mediated Modulation of Immune Response against Virus Infection -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Help …

Integrated serum pharmacochemistry and investigation of the anti-influenza A virus pneumonia effect of Qingjin Huatan decoction

M Liu, Z Li, Q Cui, B Yan, JG Achi, Y Zhao… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Qingjin Huatan Decoction (QJHTT) consists of 11
herbal medicines: Scutellaria baicalensis Georgi, Gardenia jasminoides J. Ellis, Platycodon …

Uptake pathways of cell-penetrating peptides in the context of drug delivery, gene therapy, and vaccine development

M Dowaidar - Cellular Signalling, 2024 - Elsevier
Cell-penetrating peptides have been extensively utilized for the purpose of facilitating the
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …

[HTML][HTML] Nucleoprotein as a Promising Antigen for Broadly Protective Influenza Vaccines

A Rak, I Isakova-Sivak, L Rudenko - Vaccines, 2023 - mdpi.com
Annual vaccination is considered as the main preventive strategy against seasonal
influenza. Due to the highly variable nature of major viral antigens, such as hemagglutinin …

Universal influenza vaccine technologies and recombinant virosome production

A Khalaj-Hedayati, CLL Chua, P Smooker… - Methods in …, 2022 - Elsevier
Influenza A virus poses a serious threat to human health, causing more than 650,000 deaths
annually. While flu vaccines are effective in preventing infection, high rates of antigenic …