Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Thyroid function affects multiple sites of the female hypothalamic-pituitary gonadal (HPG)
axis. Disruption of thyroid function has been linked to reproductive dysfunction in women …

Hypothyroidism is a relatively common finding during pregnancy. This may be due either to
the presence of existing thyroid disease and/or to the increased demands that pregnancy …

Thyroid hormones and iodine are required to increase basal metabolic rate and to regulate
protein synthesis, long bone growth and neuronal maturation. They are also essential for …

Comment 234 www. thelancet. com/diabetes-endocrinology Vol 10 April 2022 diseases
(simple multimorbidity), 8· 18 (7· 12–9· 39) for three diseases, and 12· 39 (9· 26–16· 58) for …

Objective Hypothyroidism has been associated with pregnancy complications, but
uncertainty prevail regarding the severity and the role of thyroid autoimmunity. This study …

Background: The relationship between isolated hypothyroxinemia (IH) in pregnancy and
adverse pregnancy outcomes is controversial, with no consensus on the need for treatment …

Objective To review the diagnosis and management of hypothyroidism during pregnancy, in
the preconception period, and in the postpartum period. Methods A literature review of …

Objective To examine the association between isolated maternal hypothyroxinaemia (IMH)
and adverse obstetric outcomes and offspring outcomes and also investigate the effects of …

Background Metabolic diseases during pregnancy result in negative consequences for
mothers. Pre-pregnancy body mass index (BMI) and late-pregnancy glycated-hemoglobin …