Genomic instability and genetic mutations can lead to exhibition of several cancer hallmarks
in affected cells such as sustained proliferative signaling, evasion of growth suppression …

Abstract Human Endogenous Retroviruses (HERVs) are viral sequences integrated into the
human genome, resulting from the infection of human germ‐line cells by ancient exogenous …

Human endogenous retroviruses (HERVs) are ancestral viral relics that constitute nearly 8%
of the human genome. Although normally silenced, the most recently integrated provirus …

Simple Summary Nuclear protein 1 (NUPR1) is activated in cellular stress and is expressed
at high levels in cancer cells. Much evidence has been gathered supporting its critical role in …

Stress contributes to the development of many human diseases, including cancer. Based on
the source of stress, it can be divided into external stress, such as environmental …

The human genome contains many retroviral elements called human endogenous
retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution …

Transactive response DNA binding protein 43 kDa (TDP-43) was discovered in 2001 as a
cellular factor capable to inhibit HIV-1 gene expression. Successively, it was brought to new …

Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections that
have become fixed in the human genome. While HERV genes are typically silenced in …

Simple Summary In its early stages, colorectal cancer (CRC) is a localized tumor, but when it
metastasizes, it has dramatic consequences. Murine models in CRC research are important …

The footprint of human endogenous retroviruses (HERV), specifically HERV-K, has been
found in malignancies, such as melanoma, teratocarcinoma, osteosarcoma, breast cancer …