Biomarkers for Alzheimer's disease diagnosis

V Mantzavinos, A Alexiou - Current Alzheimer Research, 2017 - ingentaconnect.com
Objective: The dramatic increase in the population with dementia expected in the next
decades is accompanied by the establishment of novel and innovated methods that will offer …

Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia

JC de La Torre - Cardiovascular psychiatry and neurology, 2012 - Wiley Online Library
Heart disease is the major leading cause of death and disability in the world. Mainly
affecting the elderly population, heart disease and its main outcome, cardiovascular …

Age-related normative changes in phasic orthostatic blood pressure in a large population study: findings from The Irish Longitudinal Study on Ageing (TILDA)

C Finucane, MDL O'Connell, CW Fan, GM Savva… - Circulation, 2014 - Am Heart Assoc
Background—In this report, we provide the first normative reference data and prevalence
estimates of impaired orthostatic blood pressure (BP) stabilization, initial orthostatic …

Alzheimer's disease: the link between amyloid-β and neurovascular dysfunction

E Solis Jr, KN Hascup… - Journal of Alzheimer's …, 2020 - content.iospress.com
While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Blood pressure regulation IX: cerebral autoregulation under blood pressure challenges

YC Tzeng, PN Ainslie - European journal of applied physiology, 2014 - Springer
Cerebral autoregulation (CA) is integral to the delicate process of maintaining stable
cerebral perfusion and brain tissue oxygenation against changes in arterial blood pressure …

Alzheimer's disease

C Oboudiyat, H Glazer, A Seifan, C Greer… - Seminars in …, 2013 - thieme-connect.com
Alzheimer's disease (AD) is the most common neurodegenerative cause of dementia and is
responsible for significant individual morbidity and mortality, and economic impact on the …

The association of cardiovascular disorders and falls: a systematic review

S Jansen, J Bhangu, S de Rooij, J Daams… - Journal of the American …, 2016 - Elsevier
Objective Cardiovascular disorders are recognized as risk factors for falls in older adults.
The aim of this systematic review was to identify cardiovascular disorders that are …

Chronic hypertension leads to neurodegeneration in the TgSwDI mouse model of Alzheimer's disease

A Kruyer, N Soplop, S Strickland, EH Norris - Hypertension, 2015 - Am Heart Assoc
Numerous epidemiological studies link vascular disorders, such as hypertension, diabetes
mellitus, and stroke, with Alzheimer's disease (AD). Hypertension, specifically, is an …

Assessing premorbid cognitive ability in adults with type 2 diabetes mellitus—a review with implications for future intervention studies

RHX Wong, A Scholey, PRC Howe - Current diabetes reports, 2014 - Springer
Associations between type 2 diabetes mellitus (T2DM) and accelerated cognitive decline
are well established. However, the sensitivity of neuropsychological tests to detect early …

Effects of hypertension on Alzheimer's disease and related disorders

JE Malone, MI Elkasaby, AJ Lerner - Current Hypertension Reports, 2022 - Springer
Abstract Purpose of Review To review the pathophysiology of hypertension in Alzheimer's
disease and related dementias and explore the current landscape of clinical trials involving …