Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …

Stenvinkel P (Division of Renal Medicine, Department of Clinical Science, Intervention and
Technology, Karolinska Institutet, Stockholm, Sweden). Chronic kidney disease: a public …

Significance: Reactive oxygen species (ROS) are signaling molecules that are important in
physiological processes, including host defense, aging, and cellular homeostasis. Increased …

An abrupt change in serum creatinine, the most common indicator of acute kidney injury
(AKI), is strongly linked to poor outcomes across multiple clinical settings. Despite endless …

The prevalence of chronic kidney disease (CKD) is increasing and frequently progresses to
end-stage renal disease. There is an urgent demand to discover novel markers of disease …

Background. The kidney plays a central role in elimination of metabolic waste products and
regulation of low-molecular weight metabolites via glomerular filtration, tubular secretion …

Diabetic nephropathy is the most common and most rapidly growing cause of end-stage
renal failure in developed countries. Diabetic nephropathy results from complex interactions …

Kidney diseases manifest in progressive loss of renal function, which ultimately leads to
complete kidney failure. The mechanisms underlying the origins and progression of kidney …

The kidney is a common “victim organ” of various insults in critically ill patients. Sepsis and
septic shock are the dominant causes of acute kidney injury, accounting for nearly 50% of …

Early identification and prognostic stratification of delayed graft function following renal
transplantation has significant potential to improve outcome. Mass spectrometry analysis of …