The burden of disease in rheumatoid arthritis

T Uhlig, RH Moe, TK Kvien - Pharmacoeconomics, 2014 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease which, if left untreated, leads to
functional disability, pain, reduced health-related quality of life and premature mortality …

The burden of illness of rheumatoid arthritis

A Boonen, JL Severens - Clinical rheumatology, 2011 - Springer
It is necessary to understand the full burden of illness of a disease before the value of
interventions can be assessed. Rheumatoid arthritis (RA) has an impact on a variety of …

Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a …

P Emery, FC Breedveld, S Hall, P Durez, DJ Chang… - The Lancet, 2008 - thelancet.com
Background Remission and radiographic non-progression are goals in the treatment of early
rheumatoid arthritis. The aim of the combination of methotrexate and etanercept in active …

Prevalence and predictors of disability in valued life activities among individuals with rheumatoid arthritis

PP Katz, A Morris, EH Yelin - Annals of the rheumatic diseases, 2006 - ard.bmj.com
Objective: To identify the prevalence of disability in a wide range of life activities and identify
factors associated with such disability using the Verbrugge and Jette disablement model as …

Effect of the early use of the anti–tumor necrosis factor adalimumab on the prevention of job loss in patients with early rheumatoid arthritis

V Bejarano, M Quinn, PG Conaghan… - Arthritis Care & …, 2008 - Wiley Online Library
Objective To compare work disability and job loss in early rheumatoid arthritis (RA) patients
receiving adalimumab plus methotrexate (adalimumab+ MTX) versus MTX alone. Methods …

Rheumatoid arthritis and work: the impact of rheumatoid arthritis on absenteeism and presenteeism

SMM Verstappen - Best Practice & Research Clinical Rheumatology, 2015 - Elsevier
For patients with rheumatoid arthritis (RA), being in paid work is very important, and it
increases self-esteem and financial independence. Although the management of RA has …

Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis

RCM Ho, EHY Fu, ANC Chua… - … journal of rheumatic …, 2011 - Wiley Online Library
Aim: To assess the frequency of, and factors associated with, depression and anxiety in
Singaporean patients with rheumatoid arthritis (RA). Method: One hundred RA patients were …

14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

WP Maksymowych, D van der Heijde, CF Allaart… - Arthritis research & …, 2014 - Springer
Introduction The aim of this study was to investigate whether 14-3-3η, a specific isoform of a
family of proteins regulating processes such as cellular signalling, activates cell-signalling …

Employment of patients with rheumatoid arthritis-a systematic review and meta-analysis

L Kirkeskov, K Bray - BMC rheumatology, 2023 - Springer
Background Patients with rheumatoid arthritis (RA) have difficulties maintaining employment
due to the impact of the disease on their work ability. This review aims to investigate the …

[HTML][HTML] Health Assessment Questionnaire disability progression in early rheumatoid arthritis: systematic review and analysis of two inception cohorts

S Norton, B Fu, DL Scott, C Deighton… - Seminars in arthritis and …, 2014 - Elsevier
Abstract Objective The Health Assessment Questionnaire is widely used for patients with
inflammatory polyarthritis (IP) and its subset, rheumatoid arthritis (RA). In this study, we …