[HTML][HTML] Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity

X Meng, Y Fang, M Ding, Y Zhang, K Jia, Z Li… - Biotechnology …, 2022 - Elsevier
Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

The confluence of big data and evolutionary genome mining for the discovery of natural products

MG Chevrette, A Gavrilidou, S Mantri… - Natural product …, 2021 - pubs.rsc.org
This review covers literature between 2003–2021 The development and application of
genome mining tools has given rise to ever-growing genetic and chemical databases and …

Correlative metabologenomics of 110 fungi reveals metabolite–gene cluster pairs

LK Caesar, FA Butun, MT Robey, NJ Ayon… - Nature chemical …, 2023 - nature.com
Natural products research increasingly applies-omics technologies to guide molecular
discovery. While the combined analysis of genomic and metabolomic datasets has proved …

Post‐translational modifications drive secondary metabolite biosynthesis in Aspergillus: a review

K Yang, J Tian, NP Keller - Environmental Microbiology, 2022 - Wiley Online Library
Post‐translational modifications (PTMs) are important for protein function and regulate
multiple cellular processes and secondary metabolites (SMs) in fungi. Aspergillus species …

Biosynthesis of selenium nanoparticles by Aspergillus flavus and Candida albicans for antifungal applications

MH Bafghi, M Darroudi, M Zargar… - Micro & Nano …, 2021 - Wiley Online Library
Biosynthesis of nanoparticles can replace the available chemical and physical methods by
offering new procedures as green syntheses that have proved to be simple, biocompatible …

A monograph of Aspergillus section Candidi

K Glässnerová, F Sklenář, Ž Jurjević… - Studies in …, 2022 - ingentaconnect.com
Aspergillus section Candidi encompasses white-or yellow-sporulating species mostly
isolated from indoor and cave environments, food, feed, clinical material, soil and dung …

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its close relatives

EA Hatmaker, M Rangel-Grimaldo, HA Raja… - Microbiology …, 2022 - Am Soc Microbiol
Fungal diseases affect millions of humans annually, yet fungal pathogens remain
understudied. The mold Aspergillus flavus can cause both aspergillosis and fungal keratitis …

Pangenomics of the death cap mushroom Amanita phalloides, and of Agaricales, reveals dynamic evolution of toxin genes in an invasive range

MT Drott, SC Park, Y Wang, L Harrow… - The ISME …, 2023 - academic.oup.com
Abstract The poisonous European mushroom Amanita phalloides (the “death cap”) is
invading California. Whether the death caps' toxic secondary metabolites are evolving as it …

Chromosome assembled and annotated genome sequence of Aspergillus flavus NRRL 3357

JM Skerker, KM Pianalto, SJ Mondo, K Yang, AP Arkin… - G3, 2021 - academic.oup.com
Aspergillus flavus is an opportunistic pathogen of crops, including peanuts and maize, and
is the second leading cause of aspergillosis in immunocompromised patients. A. flavus is …

A genomic journey in the secondary metabolite diversity of fungal plant and insect pathogens: From functional to population genomics

E Kuhnert, J Collemare - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Pathogenic fungi produce secondary metabolites (SMs) to control the host and its
environment.•Functional genomics facilitates identification of new SM effectors.•Population …