The emerging antioxidant paradigm of mesenchymal stem cell therapy
Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for
the treatment of diverse diseases, with many promising outcomes achieved in animal …
the treatment of diverse diseases, with many promising outcomes achieved in animal …
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives
Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …
Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
Y Zhou, H Xu, W Xu, B Wang, H Wu, Y Tao… - Stem cell research & …, 2013 - Springer
Introduction Administration of bone marrow mesenchymal stem cells (MSCs) or secreted
microvesicles improves recovery from acute kidney injury (AKI). However, the potential roles …
microvesicles improves recovery from acute kidney injury (AKI). However, the potential roles …
Adipose tissue‐derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis
A Eirin, XY Zhu, JD Krier, H Tang, KL Jordan… - Stem …, 2012 - academic.oup.com
Reno‐protective strategies are needed to improve renal outcomes in patients with
atherosclerotic renal artery stenosis (ARAS). Adipose tissue‐derived mesenchymal stem …
atherosclerotic renal artery stenosis (ARAS). Adipose tissue‐derived mesenchymal stem …
Cell-based therapy for acute organ injury: preclinical evidence and ongoing clinical trials using mesenchymal stem cells
Critically ill patients often suffer from multiple organ failures involving lung, kidney, liver, or
brain. Genomic, proteomic, and metabolomic approaches highlight common injury …
brain. Genomic, proteomic, and metabolomic approaches highlight common injury …
From AKI to CKD: maladaptive repair and the underlying mechanisms
Z Wang, C Zhang - International journal of molecular sciences, 2022 - mdpi.com
Acute kidney injury (AKI) is defined as a pathological condition in which the glomerular
filtration rate decreases rapidly over a short period of time, resulting in changes in the …
filtration rate decreases rapidly over a short period of time, resulting in changes in the …
Stem/progenitor cell in kidney: characteristics, homing, coordination, and maintenance
J Huang, Y Kong, C Xie, L Zhou - Stem Cell Research & Therapy, 2021 - Springer
Renal failure has a high prevalence and is becoming a public health problem worldwide.
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …
However, the renal replacement therapies such as dialysis are not yet satisfactory for its …
Mesenchymal stem cells and the lung
K Sinclair, ST Yerkovich, DC Chambers - Respirology, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are a population of tissue‐resident adult progenitor cells
that were originally identified in bone marrow, but have now been identified in many organs …
that were originally identified in bone marrow, but have now been identified in many organs …
[HTML][HTML] In a Phase 1a escalating clinical trial, autologous mesenchymal stem cell infusion for renovascular disease increases blood flow and the glomerular filtration …
Atherosclerotic renovascular disease (ARVD) reduces tissue perfusion and eventually leads
to loss of kidney function with limited therapeutic options. Here we describe results of Phase …
to loss of kidney function with limited therapeutic options. Here we describe results of Phase …
The anti-inflammatory, anti-oxidative, and anti-apoptotic benefits of stem cells in acute ischemic kidney injury
Ischemia-reperfusion injury (IRI) plays a significant role in the pathogenesis of acute kidney
injury (AKI). The complicated interaction between injured tubular cells, activated endothelial …
injury (AKI). The complicated interaction between injured tubular cells, activated endothelial …