Selecting candidates for drug developments using computational design and empirical rules
has resulted in a broad discussion about their success. In a previous study, we had shown …

Terpenoids, the most abundant compounds in natural products, are a set of important
secondary metabolites in plants with diverse structures. Terpenoids play key roles in plant …

The rising burden of cancer worldwide calls for an alternative treatment solution. Herbal
medicine provides a very feasible alternative to western medicine against cancer. This …

The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

Covering: 2000 to 2020 Triptolide is a bioactive diterpene triepoxide isolated from
Tripterygium wilfordii Hook F, a traditional Chinese medicinal plant whose extracts have …

Background Aptamer has been called “chemical antibody” which displays the specific affinity
to target molecules compared to that of antibodies and possesses several therapeutic …

Background Hypertension is a major public health problem worldwide. It is an important risk
factor for other cardiovascular diseases such as coronary artery disease, stroke, heart …

Oral cancer, as one of the most prevalent and invasive cancers that invade local tissue, can
cause metastasis, and have high mortality. In 2018, around 355,000 worldwide oral cancers …

Covering: 1972 to 2011 Triptolide, a principal bioactive ingredient of Tripterygium wilfordii
Hook F, has attracted extensive exploration due to its unique structure of a diterpenoid …

Celastrol, a quinone methide triterpene, is a pharmacologically active compound present in
Thunder God Vine root extracts used as a remedy of inflammatory and autoimmune …