Managing women of childbearing age with chronic myeloid leukemia: safety and treatment considerations
HF Robertson, MJ Buckton… - Expert Review of …, 2023 - Taylor & Francis
Introduction TKIs are paradigmatic in CML management and offer patients the prospect of a
normal life expectancy. As a consequence, the focus of both the clinician and patient has …
normal life expectancy. As a consequence, the focus of both the clinician and patient has …
Perspectives on drug development for the treatment of chronic myeloid leukemia in pregnant patients and patients who are breastfeeding
JE Cortes, E Abruzzese, EH Cardonick… - Clinical Cancer …, 2024 - AACR
Tyrosine kinase inhibitors (TKI) have improved the outcome and life expectancy of patients
with chronic myeloid leukemia (CML). Patients are diagnosed with CML at younger ages …
with chronic myeloid leukemia (CML). Patients are diagnosed with CML at younger ages …
Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry
E Chelysheva, J Apperley, A Turkina, MA Yassin… - Leukemia, 2024 - nature.com
The management of chronic myeloid leukemia (CML) diagnosed during pregnancy is a rare
and challenging situation. We report the treatment and outcome of 87 cases diagnosed in …
and challenging situation. We report the treatment and outcome of 87 cases diagnosed in …
Treatment of CML in pregnancy
HF Robertson, JF Apperley - Hematology, 2022 - ashpublications.org
Since the introduction of tyrosine kinase inhibitors (TKIs) at the beginning of the millennium,
the outlook for patients with chronic myeloid leukemia (CML) has improved remarkably. As …
the outlook for patients with chronic myeloid leukemia (CML) has improved remarkably. As …
Fertility and pregnancy in chronic myeloid leukemia: real-world experience from an Indian tertiary care institution
Chronic myeloid leukemia (CML) management during pregnancy is challenging. In this
retrospective study, hospital records of CML patients treated between 2000 and 2021 were …
retrospective study, hospital records of CML patients treated between 2000 and 2021 were …
Physiologically Based Pharmacokinetic Modeling of Nilotinib for Drug‐Drug Interactions, Pediatric Patients, and Pregnancy and Lactation
XI Liu, R Leong, GJ Burckart… - The Journal of Clinical …, 2024 - Wiley Online Library
Nilotinib is a second‐generation BCR‐ABL tyrosine kinase inhibitor for the treatment of
Philadelphia chromosome‐positive chronic myeloid leukemia in both adult and pediatric …
Philadelphia chromosome‐positive chronic myeloid leukemia in both adult and pediatric …
Therapeutic drug monitoring of imatinib–how far are we in the leukemia setting?
AS Buhl Rasmussen, CL Andersen… - Expert Review of …, 2024 - Taylor & Francis
ABSTRACT Introduction Tyrosine kinase inhibitors (TKIs) have revolutionized survival rates
of chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute …
of chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute …
Landscape and Regulatory Perspective on Oncology Drugs in Pregnancy
R Leong, M Grimstein, P DeMaria… - The Journal of …, 2023 - Wiley Online Library
Cancers affecting pregnant women include breast cancer, melanoma, thyroid cancer,
cervical cancer, lymphomas, and leukemias. The medical management of cancer during …
cervical cancer, lymphomas, and leukemias. The medical management of cancer during …
SOHO State of the Art Updates and Next Questions|| Chronic Myeloid Leukemia and Pregnancy:“Per Aspera Ad Astra”
E Abruzzese, MM Trawinska, P De Fabritiis… - … Myeloma and Leukemia, 2023 - Elsevier
Chronic myeloid leukemia (CML) has evolved from an invariably fatal disease to a chronic
disorder that can be treated with targeted drugs and allows survival expectations …
disorder that can be treated with targeted drugs and allows survival expectations …
Acute leukemias in pregnant women: Results of a retrospective study at a local tertiary‐care hospital in Japan
S Kobayashi, K Biyajima, S Matsuzawa, K Sakai… - …, 2023 - Wiley Online Library
Leukemia may rarely develop in a woman during pregnancy, posing clinical challenges to
the patient, fetus, family, and medical staff managing malignancy and pregnancy. We …
the patient, fetus, family, and medical staff managing malignancy and pregnancy. We …