The cellular and molecular mechanism involved in the pathogenesis of atrial fibrosis are
highly complex. We have reviewed the literature that covers the effectors, signal transduction …

Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated
with substantial morbidity and mortality. Current treatment options for AF have significant …

Background: The role of epicardial fat (eFat)-derived extracellular vesicles (EVs) in the
pathogenesis of atrial fibrillation (AF) has never been studied. We tested the hypothesis that …

Atrial enlargement in response to pathological stimuli (eg, hypertension, mitral valve
disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude …

Since their discovery in 1993, microRNAs (miRNAs) have emerged as important regulators
of many crucial cellular processes, and their dysregulation have been shown to contribute to …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia associated with
increased morbidity and mortality. The pathophysiological mechanisms underlying the …

Atrial fibrillation (AF) causes severe cardiac dysrhythmia among patients with cardiovascular
diseases. AF increases the risk of stroke and heart failure and is a growing public health …

MicroRNAs (miRNAs) play a key role in various pathological processes like atrial fibrillation
(AF), which is a common cardiac arrhythmia. Exosomes are essential information carrier in …

Cardiovascular disease (CVD) is one of the most important diseases endangering human
life. The pathogenesis of CVDs is complex. Pyroptosis, which differs from traditional …

Atrial fibrosis influences atrial fibrillation (AF) development by transforming growth factor
beta 1 (TGF-β1)/Smad pathway. Although microRNAs are implicated in the pathogenesis of …