Flavonoids comprise a large group of structurally diverse polyphenolic compounds of plant
origin and are abundantly found in human diet such as fruits, vegetables, grains, tea, dairy …

Association of diabetes with an elevated risk of cardiac failure has been clinically evident.
Diabetes potentiates diastolic and systolic cardiac failure following the myocardial infarction …

Nowadays, diabetes and obesity are two main health-threatening metabolic disorders in the
world, which increase the risk for many chronic diseases. Apelin, a peptide hormone, exerts …

Among scaffolds used in tissue engineering, natural biomaterials such as plant-based
materials show a crucial role in cellular function due to their biocompatibility and chemical …

Diabetic cardiomyopathy (DbCM) is responsible for increased morbidity and mortality in
patients with diabetes and heart failure. However, the pathogenesis of DbCM has not yet …

Ferroptosis contributes to the pathogenesis of atrial fibrillation (AF), although the
mechanisms are still largely uncovered. The current study was designed to explore the …

Diabetes mellitus (DM) is a global health issue in the twenty-first century, and there are
numerous challenges in preventing and alleviating its chronic complications. The herb …

Tubulointerstitial fibrosis is one of the most common pathological features of diabetic
nephropathy. Autophagy, an intracellular mechanism to remove damaged or dysfunctional …

Icariin (ICA) is a natural flavonoid isolated from the traditional Chinese medicinal herb,
Epimedium brevicornu Maxim. Although previous studies have reported that ICA exhibits …

Heart failure with preserved ejection fraction (HFpEF) remains a medical anomaly that
baffles researchers and physicians alike. The overall phenotypical changes of diastolic …