Genotypic resistance testing of HIV-1 DNA in peripheral blood mononuclear cells

C Chu, D Armenia, C Walworth… - Clinical Microbiology …, 2022 - Am Soc Microbiol
SUMMARY HIV-1 DNA exists in nonintegrated linear and circular episomal forms and as
integrated proviruses. In patients with plasma viremia, most peripheral blood mononuclear …

HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications

VG Valcour, BT Shiramizu… - Journal of leukocyte …, 2010 - academic.oup.com
Failure of potent antiretroviral therapy to eradicate this HIV reservoir may be responsible for
the continued occurence of dementia in HIV-infected individuals. It is broadly accepted that …

LTR real‐time PCR for HIV‐1 DNA quantitation in blood cells for early diagnosis in infants born to seropositive mothers treated in HAART area (ANRS CO 01)

AF Véronique, C Marie‐Laure… - Journal of medical …, 2009 - Wiley Online Library
HIV‐1 diagnosis in babies born to seropositive mothers is one of the challenges of HIV
epidemics in children. A simple, rapid protocol was developed for quantifying HIV‐1 DNA in …

Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro

KK Koelsch, L Liu, R Haubrich, S May… - The Journal of …, 2008 - academic.oup.com
Background. In patients infected with human immunodeficiency virus type 1 (HIV-1), HIV-1
DNA persists during highly active antiretroviral treatment, reflecting long-lived cellular …

Early Levels of HIV-1 DNA in Peripheral Blood Mononuclear Cells Are Predictive of Disease Progression Independently of HIV-1 RNA Levels and CD4+ T Cell …

C Rouzioux, JB Hubert, M Burgard… - The Journal of …, 2005 - academic.oup.com
Background The objective of this work was to assess the role of human immunodeficiency
virus (HIV) reservoirs in the risk of disease progression, by studying the relationship …

Differential upregulation of CD38 on different T-cell subsets may influence the ability to reconstitute CD4+ T cells under successful highly active antiretroviral therapy

JM Benito, M López, S Lozano… - JAIDS Journal of …, 2005 - journals.lww.com
Background: Immune activation is an independent surrogate marker of CD4 T-cell depletion
in HIV-infected patients. Highly active antiretroviral therapy (HAART) reduces disease …

HIV DNA and cognition in a Thai longitudinal HAART initiation cohort: the SEARCH 001 Cohort Study

VG Valcour, BT Shiramizu, P Sithinamsuwan… - Neurology, 2009 - AAN Enterprises
Objectives: The extent to which highly active antiretroviral therapy (HAART) era cognitive
disorders are due to active processes, incomplete clearance of reservoirs, or comorbidities …

Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions

S Yerly, HF Günthard, C Fagard, B Joos, TV Perneger… - Aids, 2004 - journals.lww.com
In HIV-1-infected patients with long-term undetectable viraemia on highly active antiretroviral
treatment (HAART), we found that pre-HAART plasma viraemia and the baseline proviral …

Comparison of resistance mutation patterns in historical plasma HIV RNA genotypes with those in current proviral HIV DNA genotypes among extensively treated …

C Delaugerre, J Braun, I Charreau, S Delarue… - HIV …, 2012 - Wiley Online Library
Objectives Heavily treatment‐experienced patients with good virological control could be at
risk of virological failure on switching to a new regimen if pre‐existing drug resistance is not …

Cytomegalovirus DNA in semen and blood is associated with higher levels of proviral HIV DNA

S Gianella, CM Anderson, MV Vargas… - The Journal of …, 2013 - academic.oup.com
Over three-fourths of human immunodeficiency virus (HIV)–infected men who have sex with
men (MSM) have at least one herpesvirus detected in their semen, and cytomegalovirus …