Cancers have become one of the major public health problems, which seriously threaten the
health of the global population. Therefore, the development of early diagnosis technology …

Melanoma is a highly aggressive malignancy and early monitoring and diagnosis are
challenging at present. Tyrosinase is overexpressed in melanoma and regarded as an …

The development of antimelanogenic agents is important for the prevention of serious
aesthetic problems such as melasma, freckles, age spots and chloasma. The aim of this …

A near-infrared methylene blue-based fluorogenic probe with an on/off activation ability has
emerged as an important means to detect and monitor biological analytes and to understand …

Background The antioxidant effects of Panax ginseng have been reported in several articles;
however, little is known about the antimelanogenesis effect, skin-protective effect, and …

Little work has been conducted on the evaluation of antioxidant and antiproliferative
activities of different sesame seed varieties. This article compared the total phenolics …

Sesame (Sesamum indicum L.) seeds have been authenticated for its medicinal value in
both Chinese and Indian systems of medicine. Its numerous potential nutritional benefits are …

Melanin is synthesized through a series of interactions catalyzed by melanogenic enzymes
such as tyrosinase, dopachrome tautomerase (tyrosinase-related protein-2; TRP-2), and …

Tyrosinase (Tyr) is known as an important cancer-related biomarker, which shows significant
over-expression in malignant tumor cells, such as melanoma. Developing highly sensitive …

In our present study, the inhibitory effect of brazilein from Caesalpinia sappan on tyrosinase
activity was investigated through multi-spectroscopic and molecular docking techniques …