[HTML][HTML] Drug addiction and treatment: An epigenetic perspective
AS Koijam, KD Singh, BS Nameirakpam… - Biomedicine & …, 2024 - Elsevier
Drug addiction is a complex disease affected by numerous genetic and environmental
factors. Brain regions in reward pathway, neuronal adaptations, genetic and epigenetic …
factors. Brain regions in reward pathway, neuronal adaptations, genetic and epigenetic …
Assessing Biological Age: The Potential of ECG Evaluation Using Artificial Intelligence: JACC Family Series
F Lopez-Jimenez, S Kapa, PA Friedman… - Clinical …, 2024 - jacc.org
Biological age may be a more valuable predictor of morbidity and mortality than a person's
chronological age. Mathematical models have been used for decades to predict biological …
chronological age. Mathematical models have been used for decades to predict biological …
[HTML][HTML] Anti-Aging Strategies to Prevent Diseases: Promoting Longevity and Optimal Health
M Farrokhi, F Taheri, M Farrokhi, A Moeini… - Kindle, 2024 - preferpub.org
Anti-aging strategies extend beyond cosmetic concerns, reaching into the realm of disease
prevention, promoting longevity, and optimizing overall health. The quest for a longer …
prevention, promoting longevity, and optimizing overall health. The quest for a longer …
A Computational Approach for the Discovery of Novel DNA Methyltransferase Inhibitors
Nowadays, the explosion of knowledge in the field of epigenetics has revealed new
pathways toward the treatment of multifactorial diseases, rendering the key players of the …
pathways toward the treatment of multifactorial diseases, rendering the key players of the …
Effect of resistance training plus enriched probiotic supplement on sestrin2, oxidative stress, and mitophagy markers in elderly male Wistar rats
M Mohabbat, H Arazi - Scientific Reports, 2024 - nature.com
This study aimed to determine the effects of resistance training combined with a probiotic
supplement enriched with vitamin D and leucine on sestrin2, oxidative stress, antioxidant …
supplement enriched with vitamin D and leucine on sestrin2, oxidative stress, antioxidant …
3D-bioprinted anti-senescence organoid scaffolds repair cartilage defect and prevent joint degeneration via miR-23b/ELOVL5-mediated metabolic rewiring
Y Wang, Y You, H Chen, J Liu, Q Wu, K Dai… - Chemical Engineering …, 2024 - Elsevier
Introduction Osteoarthritis (OA) is the most prevalent degenerative disease worldwide and
commonly occurs among the elderly. At present, there is no effective treatment for OA. When …
commonly occurs among the elderly. At present, there is no effective treatment for OA. When …
The Molecular Mechanisms in Senescent Cells Induced by Natural Aging and Ionizing Radiation
M Ibragimova, A Kussainova, A Aripova, R Bersimbaev… - Cells, 2024 - mdpi.com
This review discusses the relationship between cellular senescence and radiation exposure.
Given the wide range of ionizing radiation sources encountered by people in professional …
Given the wide range of ionizing radiation sources encountered by people in professional …
Underlying Mechanisms of the Protective Effects of Lifestyle Factors in the Prevention of Age-Related Diseases
N Alcaráz, P Salcedo-Tello, R González-Barrios… - Archives of Medical …, 2024 - Elsevier
The rise in life expectancy has significantly increased the occurrence of age-related chronic
diseases, leading to escalating expenses for both society and individuals. Among the main …
diseases, leading to escalating expenses for both society and individuals. Among the main …
The evidence to date: implications of l-ascorbic acid in the pathophysiology of aging
A Sato, Y Kondo, A Ishigami - The Journal of Physiological Sciences, 2024 - Springer
L-Ascorbic acid, commonly known as vitamin C, has been used not only for disease
prevention and in complementary and alternative medicine, but also for anti-aging purposes …
prevention and in complementary and alternative medicine, but also for anti-aging purposes …
Inhibition of Mettl3 ameliorates osteoblastic senescence by mitigating m6A modifications on Slc1a5 via Igf2bp2-dependent mechanisms
XW Liu, HW Xu, YY Yi, SB Zhang, SJ Chang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Age-related osteoporosis is characterized by a marked decrease in the number of
osteoblasts, which has been partly attributed to the senescence of cells of the osteoblastic …
osteoblasts, which has been partly attributed to the senescence of cells of the osteoblastic …