Although Parkinson's disease (PD) is primarily considered a disorder of initiation of actions,
patients also have deficits in inhibitory control, both in the motor and cognitive domains …

Attention deficit hyperactivity disorder (ADHD) is now among the most commonly diagnosed
chronic psychological dysfunctions of childhood. By varying estimates, it has increased by …

Cholinergic projections to the cortex and hippocampus mediate fundamental cognitive
processes. The capacity of the high-affinity choline uptake transporter (CHT) to import …

Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …

The multifaceted concept of impulsivity implies that different impulsivity aspects, mediated by
different neural processes, influence behavior at different levels. The nucleus accumbens …

The origins and evolution of higher cognitive functions, including complex forms of learning,
attention and executive functions, are unknown. A potential mechanism driving the evolution …

BACKGROUND: Although heavy smoking has been associated with impulsivity in humans, it
is not clear whether poor impulse control represents a risk factor in the etiology of nicotine …

We describe a touchscreen method that satisfies a proposed 'wish-list'of desirables for a
cognitive testing method for assessing rodent models of schizophrenia. A number of tests …

Animal models are extremely useful tools in defining pathogenesis and treatment of human
disease. Creating adequate animal models of complex neuropsychiatric disorders such as …