Epidermolysis bullosa
A Bardhan, L Bruckner-Tuderman… - Nature Reviews …, 2020 - nature.com
Epidermolysis bullosa (EB) is an inherited, heterogeneous group of rare genetic dermatoses
characterized by mucocutaneous fragility and blister formation, inducible by often minimal …
characterized by mucocutaneous fragility and blister formation, inducible by often minimal …
Extracellular vesicles: Emerging frontiers in wound healing
Extracellular vesicles are membranous particles, ranging from 30 nm to 10 µm in diameter,
which are released by nearly all cell types to aid in intercellular communication. These …
which are released by nearly all cell types to aid in intercellular communication. These …
[HTML][HTML] Therapeutic base editing and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa
SA Hong, SE Kim, AY Lee, GH Hwang, JH Kim… - Molecular Therapy, 2022 - cell.com
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe skin fragility disorder
caused by loss-of-function mutations in the COL7A1 gene, which encodes type VII collagen …
caused by loss-of-function mutations in the COL7A1 gene, which encodes type VII collagen …
[HTML][HTML] Therapeutic features and updated clinical trials of mesenchymal stem cell (MSC)-derived exosomes
Identification of the immunomodulatory and regenerative properties of mesenchymal stem
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …
cells (MSCs) have made them an attractive alternative therapeutic option for diseases with …
Innovations in the treatment of dystrophic epidermolysis bullosa (DEB): current landscape and prospects
PC Hou, N Del Agua, SM Lwin, CK Hsu… - … and Clinical Risk …, 2023 - Taylor & Francis
Dystrophic epidermolysis bullosa (DEB) is one of the major types of EB, a rare hereditary
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …
group of trauma-induced blistering skin disorders. DEB is caused by inherited pathogenic …
[HTML][HTML] Stem cell-based therapy for pulmonary fibrosis
W Cheng, Y Zeng, D Wang - Stem Cell Research & Therapy, 2022 - Springer
Pulmonary fibrosis (PF) is a chronic and relentlessly progressive interstitial lung disease in
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …
which the accumulation of fibroblasts and extracellular matrix (ECM) induces the destruction …
[HTML][HTML] Clinical trial of ABCB5+ mesenchymal stem cells for recessive dystrophic epidermolysis bullosa
D Kiritsi, K Dieter, E Niebergall-Roth, S Fluhr… - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating,
and life-threatening inherited skin fragility disorder that comes about due to a lack of …
and life-threatening inherited skin fragility disorder that comes about due to a lack of …
Prevalence, pathophysiology and management of itch in epidermolysis bullosa
M Papanikolaou, A Onoufriadis… - British Journal of …, 2021 - academic.oup.com
Epidermolysis bullosa (EB) is a highly diverse group of inherited skin disorders, resulting
from mutations in genes encoding proteins of the dermoepidermal junction. Itch (pruritus) is …
from mutations in genes encoding proteins of the dermoepidermal junction. Itch (pruritus) is …
Investigational treatments for epidermolysis bullosa
PC Hou, HT Wang, S Abhee, WT Tu… - American Journal of …, 2021 - Springer
Epidermolysis bullosa (EB) is a heterogeneous group of rare inherited blistering skin
disorders characterized by skin fragility following minor trauma, usually present since birth …
disorders characterized by skin fragility following minor trauma, usually present since birth …
[HTML][HTML] Intravenous allogeneic umbilical cord blood–derived mesenchymal stem cell therapy in recessive dystrophic epidermolysis bullosa patients
SE Lee, SJ Lee, SE Kim, K Kim, B Cho, K Roh, SC Kim - JCI insight, 2021 - ncbi.nlm.nih.gov
BACKGROUND Recessive dystrophic epidermolysis bullosa (RDEB) is an incurable
disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding …
disease that causes severe mucocutaneous fragility due to mutations in COL7A1 (encoding …