Background: Vascular permeability (VP) is a fundamental aspect of vascular biology. A
growing number of studies have revealed that many signalling pathways govern VP in both …

Peritoneal dialysis (PD) is an effective alternative treatment for patients with end-stage renal
disease (ESRD) and is increasingly being adopted and promoted worldwide. However, as …

The consumption of exogenous antioxidants isolated from herbal extracts has shown
beneficial effects on ameliorating dialysis-related complications through debilitating …

Oxidative stress plays a key role in the pathophysiology of chronic kidney disease (CKD).
Most studies have investigated peripheral redox state focus on plasma, but not in different …

Background Peritoneal fibrosis (PF) is a frequent complication caused by peritoneal dialysis
(PD). Peritoneal mesothelial cells (PMCs), the first barrier of the peritoneum, play an …

Reactive carbonyl species (RCS) such as methylglyoxal (MGO) or glyoxal (GO) are the main
precursors of the formation of advanced glycation end products (AGEs). AGEs are a major …

Chronic kidney disease (CKD) is a major public health problem worldwide and affects both
elderly and young subjects. Its main consequences include the loss of renal function …

Dialysis patients experience 10–20 times higher cardiovascular mortality than the general
population. The high burden of both conventional and nontraditional risk factors attributable …

Catestatin (CST) is a pleiotropic peptide involved in cardiovascular protection with its
antihypertensive and angiogenic effects. Considering that patients with end-stage renal …

Background. Increased oxidative stress play an important role in the risk of cardiovascular
disease, mortality, and mortality patients undergoing dialysis. Nasturtium officinale …