Opsonins and dysopsonins of nanoparticles: facts, concepts, and methodological guidelines
E Papini, R Tavano, F Mancin - Frontiers in immunology, 2020 - frontiersin.org
Understanding the effects mediated by a set of nanoparticle (NP)-bound host biomolecules,
often indicated with the umbrella term of NP corona, is essential in nanomedicine …
often indicated with the umbrella term of NP corona, is essential in nanomedicine …
The role of protein corona on nanodrugs for organ-targeting and its prospects of application
S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …
to deliver drugs to reach their destination more effectively due to their unique properties and …
The viral protein corona directs viral pathogenesis and amyloid aggregation
Artificial nanoparticles accumulate a protein corona layer in biological fluids, which
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
significantly influences their bioactivity. As nanosized obligate intracellular parasites, viruses …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Nanotechnology in the diagnosis and treatment of lung cancer
AM Cryer, AJ Thorley - Pharmacology & therapeutics, 2019 - Elsevier
Lung cancer is an umbrella term for a subset of heterogeneous diseases that are collectively
responsible for the most cancer-related deaths worldwide. Despite the tremendous progress …
responsible for the most cancer-related deaths worldwide. Despite the tremendous progress …
Robust sequential biophysical fractionation of blood plasma to study variations in the biomolecular landscape of systemically circulating extracellular vesicles across …
G Vergauwen, J Tulkens, C Pinheiro… - Journal of …, 2021 - Wiley Online Library
Separating extracellular vesicles (EV) from blood plasma is challenging and complicates
their biological understanding and biomarker development. In this study, we fractionate …
their biological understanding and biomarker development. In this study, we fractionate …
Targeting strategies for the combination treatment of cancer using drug delivery systems
J Kydd, R Jadia, P Velpurisiva, A Gad, S Paliwal, P Rai - Pharmaceutics, 2017 - mdpi.com
Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy
treatment—due to the hostile tumor microenvironment—that create a significant challenge …
treatment—due to the hostile tumor microenvironment—that create a significant challenge …
Nanoparticles for local delivery of siRNA in lung therapy
M Kubczak, S Michlewska, M Bryszewska… - Advanced Drug Delivery …, 2021 - Elsevier
An overview of the application of natural and synthetic, non-viral vectors for oligonucleotide
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …
delivery into the lung is presented in this review, with a special focus on lung cancer. Due to …
Unveiling the molecular structure of pulmonary surfactant corona on nanoparticles
The growing risk of human exposure to airborne nanoparticles (NPs) causes a general
concern on the biosafety of nanotechnology. Inhaled NPs can deposit in the deep lung at …
concern on the biosafety of nanotechnology. Inhaled NPs can deposit in the deep lung at …
[HTML][HTML] Pulmonary surfactant and nanocarriers: Toxicity versus combined nanomedical applications
Pulmonary surfactant is a membrane-based lipid-protein system essential for the process of
breathing, which coats and stabilizes the whole respiratory surface and possesses …
breathing, which coats and stabilizes the whole respiratory surface and possesses …