Circadian rhythms impact cardiac and vascular pathophysiology, resulting in 24-hour
patterning of symptoms and life-threatening/ending events (chronopathology), plus kinetics …

The conduct of molecular and laboratory animal circadian rhythm research has increased
exponentially in the past few decades, such that today investigations are being performed by …

ABSTRACT The pharmacokinetics (PK)–absorption, distribution, metabolism, and
elimination–and pharmacodynamics (PD) of hypertension medications can be significantly …

Several prospective studies consistently report elevated asleep blood pressure (BP) and
blunted sleep-time relative systolic BP (SBP) decline (non-dipping) are jointly the most …

Introduction Hypertension is a major public health problem that is often unrecognized, and
its detection and control should be prioritized. The level of undiagnosed hypertension and its …

Introduction Treatment of glaucoma and systemic hypertension requires careful balancing of
ophthalmic and systemic medications. This report offers background on various common …

Borbély proposed an interacting two‐component model of sleep regulation comprising a
homeostatic Process S and a circadian Process C. The model has provided understanding …

The participating doctors of the Hygia Chronotherapy Trial (HCT) are aware of the criticisms
of its published findings, which have been unjustifiably misrepresented in letters to the …

Pre-diabetes is the state of hyperglycemia at an intermediate stage in which parameters of
blood glucose are above standard value but less than the threshold of diabetes. Diabetes …

La hipertensión arterial (HTA) es un factor de riesgo importante para enfermedades
cardiovasculares y constituye un problema de salud pública a nivel global. Este artículo …