From pulses to pain relief: An update on the mechanisms of rTMS‐induced analgesic effects

X Moisset, DC de Andrade… - European journal of …, 2016 - Wiley Online Library
Background Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive technique
that allows cortical stimulation. Recent studies have shown that rTMS of the primary motor …

Potential mechanisms supporting the value of motor cortex stimulation to treat chronic pain syndromes

MF DosSantos, N Ferreira, RL Toback… - Frontiers in …, 2016 - frontiersin.org
Throughout the first years of the twenty-first century, neurotechnologies such as motor cortex
stimulation (MCS), transcranial magnetic stimulation (TMS), and transcranial direct current …

The Antinociceptive Properties of the Corydalis yanhusuo Extract

L Wang, Y Zhang, Z Wang, N Gong, TD Kweon, B Vo… - PloS one, 2016 - journals.plos.org
Corydalis yanhusuo. WT extracts (YHS) are widely used for the treatment of pain and
inflammation. There are a few studies that assessed the effects of YHS in pain assays; …

Variation in the dopamine D2 receptor gene plays a key role in human pain and its modulation by transcranial magnetic stimulation

SK Jääskeläinen, P Lindholm, T Valmunen, U Pesonen… - PAIN®, 2014 - Elsevier
We tested whether variation of the dopamine D2 receptor (DRD2) gene contributes to
individual differences in thermal pain sensitivity and analgesic efficacy of repetitive …

Dopaminergic and serotonergic mechanisms in the modulation of pain: In vivo studies in human brain

IK Martikainen, N Hagelberg, SK Jääskeläinen… - European Journal of …, 2018 - Elsevier
Here we review the literature assessing the roles of the brain dopaminergic and
serotonergic systems in the modulation of pain as revealed by in vivo human studies using …

Somatotopic effects of rTMS in neuropathic pain? A comparison between stimulation over hand and face motor areas

N Andre‐Obadia, M Magnin, E Simon… - … journal of pain, 2018 - Wiley Online Library
Background The therapeutic influence of somatotopic matching between pain topography
and motor cortex stimulation site for neuropathic pain (NP) remains controversial. Methods …

Pain inhibits pain: an ascending-descending pain modulation pathway linking mesolimbic and classical descending mechanisms

G Tobaldini, NF Sardi, VA Guilhen, L Fischer - Molecular neurobiology, 2019 - Springer
The ability to modulate pain perception is as critical to survival as pain itself. The most
known pain modulation pathway is the PAG–RVM (periaqueductal gray–rostral …

[HTML][HTML] Cortical stimulation for chronic pain: from anecdote to evidence

L Garcia-Larrea, C Quesada - EuropEan Journal of physical and …, 2022 - ncbi.nlm.nih.gov
Epidural stimulation of the motor cortex (eMCS) was devised in the 1990's, and has now
largely supplanted thalamic stimulation for neuropathic pain relief. Its mechanisms of action …

Systemic and peripheral mechanisms of cortical stimulation-induced analgesia and refractoriness in a rat model of neuropathic pain

DV Assis, ACP Campos, AFN Paschoa… - International journal of …, 2023 - mdpi.com
Epidural motor cortex stimulation (MCS) is an effective treatment for refractory neuropathic
pain; however, some individuals are unresponsive. In this study, we correlated the …

Sexually dimorphic response of colorectal motility to noxious stimuli in the colorectum in rats

K Horii, Y Ehara, T Shiina, K Naitou… - The Journal of …, 2021 - Wiley Online Library
Key points This study showed a remarkable sex difference in responses of colorectal motility
to noxious stimuli in the colorectum in rats: colorectal motility was enhanced in response to …