The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

Despite the ubiquitous absorption of mid-infrared (IR) radiation by virtually all molecules that
belong to the major biomolecules groups (proteins, lipids, carbohydrates, nucleic acids), the …

Abrupt aggregation of amyloid β1‐42 (Aβ) peptide is a hallmark of Alzheimer's disease (AD),
a severe pathology that affects more than 44 million people worldwide. A growing body of …

Transthyretin (TTR) is a small, β-sheet-rich tetrameric protein that transports thyroid hormone
thyroxine and retinol. Phospholipids, including phosphatidic acid (PA), can uniquely alter the …

The plasma membrane is a dynamic structure that separates the cell interior from the
extracellular space. The fluidity and plasticity of the membrane determines a large number of …

Phosphatidylserine (PS) is a negatively charged lipid that plays a critically important role in
cell apoptosis. Under physiological conditions, PS is localized on the cytosolic side of …

Alzheimer's disease (AD) is characterized by progressive memory loss and serious
impairment of cognitive abilities. AD is the most common cause of dementia, affecting more …

Abrupt aggregation of misfolded proteins is the underlying molecular cause of numerous
pathologies including diabetes type 2 and injection amyloidosis. Although the exact cause of …

Irreversible aggregation of misfolded proteins is the underlying molecular cause of
numerous pathologies, including diabetes type 2, Alzheimer's, and Parkinson's diseases …

Conspectus The abrupt aggregation of misfolded proteins is linked to the onset and spread
of amyloidogenic diseases, including diabetes type 2, systemic amyloidosis, and …