Biological potential of carbazole derivatives

A Głuszyńska - European journal of medicinal chemistry, 2015 - Elsevier
Carbazole skeleton is the key structural motif of many biologically active compounds
including synthetic and natural products. Over the past several years, a large number of …

Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention

D Tewari, SF Nabavi, SM Nabavi, A Sureda… - Pharmacological …, 2018 - Elsevier
Abstract Activator protein 1 (AP-1) is a key transcription factor in the control of several
cellular processes responsible for cell survival proliferation and differentiation. Dysfunctional …

(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis

M Wang, CY Liu, T Wang, HM Yu, SH Ouyang… - Cell death & …, 2020 - nature.com
Drug-induced liver injury is the major cause of acute liver failure. However, the underlying
mechanisms seem to be multifaceted and remain poorly understood, resulting in few …

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways

C Mi, J Ma, KS Wang, HX Zuo, Z Wang, MY Li… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Angelica dahurica is a commonly used traditional Chinese
medicine to treat migraine headache, toothache and cancer. Imperatorin is an active natural …

Evaluation of Ethnomedical Claim III: Anti‐hyperglycemic activities of Gongronema latifolium root and stem (民族药物需求评估III:Gongronema latifolium根与茎的降糖 …

AC Adebajo, MD Ayoola, SA Odediran… - Journal of …, 2013 - Wiley Online Library
摘要背景为了证实非洲民族医药在糖尿病治疗中的作用, 评估了Gongronema latifolium
(萝藦科) 的根与茎组合是否具有促胰岛素分泌的活性作用. 方法检测其甲醇提取物以及它的色谱 …

Antioxidant and anticancer activities of 8-hydroxypsoralen isolated from wampee [Clausena lansium (Lour.) Skeels] peel

KN Prasad, H Xie, J Hao, B Yang, S Qiu, X Wei, F Chen… - Food chemistry, 2010 - Elsevier
Fruits of wampee [Clausena lansium (Lour.) Skeels] contain a significant amount of
coumarins with many health benefits. The activity-guided separation of an ethyl acetate …

African medicinal plants with antidiabetic potentials: A review

A Mohammed, MA Ibrahim, MS Islam - Planta Medica, 2014 - thieme-connect.com
Diabetes mellitus is one of the major health problems in Africa. The conventional oral
synthetic antidiabetic drugs available to manage the disease are costly and not readily …

The α-amylase and α-glucosidase inhibitory activities of the dichloromethane extracts and constituents of Ferulago bracteata roots

S Karakaya, S Gözcü, Z Güvenalp, H Özbek… - Pharmaceutical …, 2018 - Taylor & Francis
Abstract Context: Ferulago (Apiaceae) species have been used since ancient times for the
treatment of intestinal worms, hemorrhoids, and as a tonic, digestive, aphrodisiac, or …

Comprehensive Review of Phytochemical Profiles and Health-Promoting Effects of Different Portions of Wampee (Clausena lansium)

X Huang, M Wang, S Zhong, B Xu - ACS omega, 2023 - ACS Publications
Clausena lansium, commonly known as wampee, is a subtropical fruit from the Rutaceae
family characterized by its high nutrient content and numerous bioactive substances. This …

Claurailas A−D, Cytotoxic Carbazole Alkaloids from the Roots of Clausena harmandiana

U Songsiang, T Thongthoom… - Journal of natural …, 2011 - ACS Publications
Four new carbazole alkaloids, claurailas A− D (1− 4), as well as 12known carbazoles and
three known coumarins were isolated from the roots of Clausena harmandiana …