Indications and limitations of chemotherapy and targeted agents in non-small cell lung cancer brain metastases

S Zimmermann, R Dziadziuszko, S Peters - Cancer treatment reviews, 2014 - Elsevier
Lung cancer is characterized by the highest incidence of solid tumor-related brain
metastases, which are reported with a growing incidence during the last decade. Prognostic …

[HTML][HTML] Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of central nervous system metastases from non-small cell lung cancer: the present …

C Proto, M Imbimbo, R Gallucci, A Brissa… - … lung cancer research, 2016 - ncbi.nlm.nih.gov
Lung cancer is one of the major causes of cancer related mortality worldwide. Brain
metastases (BM) complicate clinical evolution of non-small cell lung cancer (NSCLC) in …

Clinical outcome in patients with leptomeningeal metastasis from non-small cell lung cancer: Okayama Lung Cancer Study Group

S Umemura, K Tsubouchi, H Yoshioka, K Hotta… - Lung Cancer, 2012 - Elsevier
OBJECTIVE: We examined the prognosis of patients with leptomeningeal metastasis (LM)
from non-small cell lung cancer (NSCLC) and that stratified by epidermal growth factor …

Molecular subtyping of brain metastases and implications for therapy

JJ Renfrow, GJ Lesser - Current treatment options in oncology, 2013 - Springer
Opinion statement Molecular subtyping of tumors and treatment with specifically targeted
therapy is a rapidly developing trend in oncology. Genetic and protein biomarkers impact …

Management of CNS metastases in patients with EGFR mutation-positive NSCLC

V Shetty, S Babu - Indian Journal of Cancer, 2019 - journals.lww.com
Central nervous system (CNS) metastases are a frequent and severe complication
associated with epidermal growth factor receptor (EGFR)-mutated non-small cell lung …

Novel systemic treatments for brain metastases from lung cancer

B Thapa, A Lauko, K Desai, VA Venur… - … Treatment Options in …, 2018 - Springer
Purpose of review Brain metastases are frequent complication of lung cancer and are
associated with poor prognosis. Patients with brain metastases secondary to lung cancer …

Recurrent response to advanced lung adenocarcinoma with erlotinib developing leptomeningeal metastases during gefitinib therapy and two case reports

P Xing, J Li, Y Shi, X Zhang - Thoracic Cancer, 2014 - Wiley Online Library
Background Epidermal growth factor‐tyrosine kinase inhibitors (EGFR‐TKIs) are one of the
effective medicines in advanced lung adenocarcinoma leptomeningeal metastasis (LM) …

[HTML][HTML] Current progress and outcomes of clinical trials on using epidermal growth factor receptor-tyrosine kinase inhibitor therapy in non-small cell lung cancer …

LL Kong, LL Wang, LG Xing, JM Yu - Chronic Diseases and Translational …, 2017 - Elsevier
Non-small cell lung cancer (NSCLC) continues to be one of the major causes of cancer-
related deaths worldwide, and brain metastases are the major cause of death in NSCLC …

[PDF][PDF] 厄洛替尼单药与替莫唑胺联合放疗对肺腺癌伴脑转移的临床疗效分析

江昊, 李娈, 邓鹏, 张斌, 周涛, 董岩 - 现代生物医学进展, 2014 - biomed.cnjournals.com
摘要目的: 探讨厄洛替尼单药与替莫唑胺联合放疗治疗肺腺癌脑转移的有效性和安全性. 方法:
选择2009 年1 月~ 2011 年12 月我院收治的54 例肺癌脑转移患者为研究对象 …

临床药师基于循证方法对1 例晚期肺癌脑转移患者的药学监护

寇温, 武新安, 孙路路, 谢铮铮 - 2014 - ir.lzu.edu.cn
摘要目的: 通过临床药师基于循证方法对1 例肺癌伴脑转移患者实施药学监护,
探讨临床药师如何应用文献证据为临床提供治疗建议, 更好地发挥临床药师的作用. 方法 …