Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases

YM Ma, L Zhao - Behavioural Neurology, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in
animals and plants. They can inhibit translation or overexpression by combining with mRNA …

RNA Landscapes of Brain and Brain-Derived Extracellular Vesicles in Simian Immunodeficiency Virus Infection and Central Nervous System Pathology

Y Huang, A Abdelgawad, A Turchinovich… - The Journal of …, 2024 - academic.oup.com
Background Brain tissue-derived extracellular vesicles (bdEVs) act locally in the central
nervous system (CNS) and may indicate molecular mechanisms in human …

Small RNA Changes in Plasma Have Potential for Early Diagnosis of Alzheimer's Disease before Symptom Onset

J Palade, E Alsop, A Courtright-Lim, M Hsieh… - Cells, 2024 - mdpi.com
Alzheimer's disease (AD), due to its multifactorial nature and complex etiology, poses
challenges for research, diagnosis, and treatment, and impacts millions worldwide. To …

The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling

BL dos Santos, CC dos Santos, KC da Silva… - International Journal of …, 2024 - mdpi.com
MicroRNAs (miRs) act as important post-transcriptional regulators of gene expression in
glial cells and have been shown to be involved in the pathogenesis of neurodegenerative …

[HTML][HTML] RNA landscapes of brain tissue and brain tissue-derived extracellular vesicles in simian immunodeficiency virus (SIV) infection and SIV-related central …

Y Huang, A Abdelgawad, A Turchinovich, S Queen… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Methods: Postmortem occipital cortex tissue were collected from pigtailed macaques:
uninfected controls and SIV-infected subjects (acute phase and chronic phase with or …

[PDF][PDF] MAJOR ARTICLE

Y Huang, A Abdelgawad, A Turchinovich, S Queen… - 2023 - researchgate.net
Methods: Postmortem occipital cortex samples were obtained from uninfected controls and
SIV-infected subjects (acute and chronic phases with or without CNS pathology (SIV …