[HTML][HTML] Inducible nitric oxide synthase is present in human abdominal aortic aneurysm and promotes oxidative vascular injury

J Zhang, J Schmidt, E Ryschich… - Journal of vascular …, 2003 - Elsevier
OBJECTIVE: Nitric oxide (NO), catalyzed by inducible NO synthase (iNOS), may be
important in the pathophysiologic characteristics of many vascular diseases. Although there …

Quercetin, a flavonoid with anti-inflammatory activity, suppresses the development of abdominal aortic aneurysms in mice

L Wang, B Wang, H Li, H Lu, F Qiu, L Xiong… - European Journal of …, 2012 - Elsevier
Inflammation has been implicated as a contributing factor in the development of abdominal
aortic aneurysms (AAA). Quercetin, a natural flavonoid with anti-inflammatory properties, is …

Wall stress studies of abdominal aortic aneurysm in a clinical model

MJ Thubrikar, J Al-Soudi, F Robicsek - Annals of vascular surgery, 2001 - Elsevier
To estimate when an abdominal aortic aneurysm (AAA) may rupture, it is necessary to
understand the forces responsible for this event. We investigated the wall stresses in an AAA …

Cytokines as plasma markers of abdominal aortic aneurysm

V Třeška, O Topolčan, L Pecen - 2000 - degruyter.com
The pathogenesis of abdominal aortic aneurysms (AAA) is a complex process in which
atherosclerosis and inflammation play a leading role. Cytokines are important mediators of …

Detection of viable chlamydia pneumoniae inAbdominal aortic aneurysms

L Karlsson, J Gnarpe, J Nääs, G Olsson… - European Journal of …, 2000 - Elsevier
Objectives to investigate the presence of Chlamydia pneumoniae in the wall of abdominal
aortic aneurysms (AAAs) and in the aortas of patients without a history of cardiovascular …

Inflammation in the wall of abdominal aortic aneurysm and its role in the symptomatology of aneurysm

V Treska, J Kocova, L Boudova… - Cytokines, cellular & …, 2002 - Taylor & Francis
Cytosol levels of cytokines [interleukins 1b, 6, 8 (IL-1b, 6, 8), tumor necrosis factor-α (TNF-α)]
in aneurysm walls were evaluated in a prospective non-randomized study of 57 patients …

Controlling the expansion of abdominal aortic aneurysms

MM Thompson - Journal of British Surgery, 2003 - academic.oup.com
Controlling the expansion of abdominal aortic aneurysms | British Journal of Surgery | Oxford
Academic Skip to Main Content Advertisement intended for healthcare professionals Oxford …

The role of matrix metalloproteinases in vascular disease

IM Loftus, MM Thompson - Vascular Medicine, 2002 - journals.sagepub.com
There is growing interest in the role of matrix metalloproteinasesin vascular diseases. These
conditions are often characterized by excessive tissue remodelling, and increased matrix …

Pro‐elastogenic effects of bone marrow mesenchymal stem cell‐derived smooth muscle cells on cultured aneurysmal smooth muscle cells

G Swaminathan, VS Gadepalli, I Stoilov… - Journal of tissue …, 2017 - Wiley Online Library
Abdominal aortic aneurysms (AAAs) involve slow proteolysis and loss of structural matrix
components (collagen and elastin), which lead to wall thinning, weakening and ultimate …

Targeting epidermal growth factor receptor to stimulate elastic matrix regenerative repair

S Dayal, T Broekelmann, RP Mecham… - … Engineering Part A, 2023 - liebertpub.com
Abdominal aortic aneurysms (AAAs) represent a multifactorial, proteolytic disorder involving
disintegration of the matrix structure within the AAA wall. Intrinsic deficiency of adult vascular …