Chlamydia pneumoniae in Abdominal Aortic Aneurysms: Abundance of Membrane Components in the Absence of Heat Shock Protein 60 and DNA

A Meijer, JA van der Vliet, PJM Roholl… - … , and vascular biology, 1999 - Am Heart Assoc
In this article, we describe the results of a comparative study for the detection of Chlamydia
pneumoniae in abdominal aortic aneurysm specimens of 19 patients through the use of …

Increased apoptosis and decreased density of medial smooth muscle cells in human abdominal aortic aneurysms

J Zhang, J Schmidt, E Ryschich… - Chinese medical …, 2003 - mednexus.org
Objective To determine the increase of apoptosis and the decrease of smooth muscle cells
(SMCs) density in human abdominal aortic aneurysms (AAA). Methods In situ terminal …

Deciphering the Intercellular Communication Between Immune Cells and Altered Vascular Smooth Muscle Cell Phenotypes in Aortic Aneurysm From Single-Cell …

G Cao, Z Lu, R Gu, X Xuan, R Zhang, J Hu… - Frontiers in …, 2022 - frontiersin.org
Background Vascular smooth muscle cell (VSMC) phenotype switching has been
preliminarily found in aortic aneurysms. However, two major questions were raised:(1) What …

Inhibition of AAA in a rat model by treatment with ACEI perindopril

F Xiong, J Zhao, G Zeng, B Huang, D Yuan… - Journal of Surgical …, 2014 - Elsevier
Background The purpose of the present study was to evaluate the effect of a new
angiotensin converting enzyme inhibitor perindopril on the formation of experimental …

Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease

GD Treharne, JR Boyle, S Goodall… - Journal of British …, 1999 - academic.oup.com
Background Abdominal aortic aneurysms are characterized by degradation of the
extracellular matrix, with a reduction in the elastin concentration of the arterial media. These …

Matrix metalloproteinase-9 expression after myocardial infarction: physiological or pathological?

MM Thompson, IB Squire - Cardiovascular research, 2002 - academic.oup.com
See article by Romanic et al.[24](pages 549–558) in composition of the vasculature are the
collagenases and this issue. gelatinases. The collagenases (MMP-1,-8 and-13) have the …

[HTML][HTML] Aminoterminal propeptide of type III procollagen and matrix metalloproteinases-2 and-9 failed to serve as serum markers for abdominal aortic aneurysm

T Eugster, A Huber, T Obeid, I Schwegler… - European Journal of …, 2005 - Elsevier
OBJECTIVES: Matrix-metalloproteinase (MMP)-2 and-9 and aminoterminal propeptide of
type III collagen (NIIINP) have been reported to be elevated in patients with abdominal aortic …

The creation of an infrarenal aneurysm within the native abdominal aorta of swine

RL Hynecek, BG DeRubertis, SM Trocciola, H Zhang… - Surgery, 2007 - Elsevier
BACKGROUND: Models of native abdominal aortic aneurysms (AAA) have been created in
rodents using elastase and calcium chloride perfusion. These models, however, do not …

Protein kinase C δ regulates the release of collagen type I from vascular smooth muscle cells via regulation of Cdc42

J Lengfeld, Q Wang, A Zohlman… - Molecular biology of …, 2012 - Am Soc Cell Biol
Collagen type I is the most abundant component of extracellular matrix in the arterial wall.
Mice knocked out for the protein kinase C δ gene (PKCδ KO) show a marked reduction of …

Assessing trans‐endothelial transport of nanoparticles for delivery to abdominal aortic aneurysms

J Yau, P Chukwu, SS Jedlicka… - Journal of Biomedical …, 2024 - Wiley Online Library
Abdominal aortic aneurysms (AAAs) are localized, rupture‐prone expansions of the
abdominal aorta wall. In this condition, structural extracellular matrix (ECM) proteins of the …