Induced elastin regeneration by chronically activated smooth muscle cells for targeted aneurysm repair

CR Kothapalli, A Ramamurthi - Acta biomaterialia, 2010 - Elsevier
Elastin breakdown in vascular aneurysms is mediated by cytokines such as tumor necrosis
factor α (TNF-α, which induces vascular smooth muscle cell (SMC) activation and regulates …

The association of serum thrombomodulin with endothelial injuring factors in abdominal aortic aneurysm

M Budzyń, B Gryszczyńska, W Majewski… - BioMed Research …, 2017 - Wiley Online Library
Background. The aim of the present study was to evaluate the concentration of serum
thrombomodulin (sTM) in the AAA patients and to examine its correlation with various factors …

Mitochondrial-dependent apoptosis in experimental rodent abdominal aortic aneurysms

I Sinha, AP Sinha-Hikim, KK Hannawa, PK Henke… - Surgery, 2005 - Elsevier
OBJECTIVES: While extrinsic mechanisms of apoptosis in abdominal aortic aneurysms
(AAAs) are recognized, this project hypothesizes that an intrinsic, mitochondrial-dependent …

Analysis of secretory group II phospholipase A2 expression in human aortic tissue in dependence on the degree of atherosclerosis

A Schiering, M Menschikowski, E Mueller, W Jaross - Atherosclerosis, 1999 - Elsevier
Secretory non-pancreatic (group II) phospholipase A2 (sPLA2) releases precursors of
important mediators of inflammation from phospholipids. Based on the inflammatory …

Changes of the infrarenal aortic segment after conventional abdominal aortic aneurysm repair

C Liapis, J Kakisis, E Kaperonis… - European Journal of …, 2000 - Elsevier
Objectives to delineate the natural history of the residual infrarenal aortic segment after
conventional abdominal aortic aneurysm (AAA) repair. Design open prospective study …

Rosiglitazone negatively regulates c-Jun N-terminal kinase and toll-like receptor 4áproinflammatory signalling during initiation of experimental aortic aneurysms

G Pirianov, E Torsney, F Howe, GW Cockerill - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: Development and rupture of aortic aneurysms (AA) is a complex process
involving inflammation, cell death, tissue and matrix remodelling. The thiazolidinediones …

Metalloproteinases, insulin‐like growth factor‐I and its binding proteins in aortic aneurysm

B Panek, M Gacko, J Pałka - International journal of …, 2004 - Wiley Online Library
Abdominal aortic aneurysm is accompanied by the impairment of collagen metabolism in
arterial wall. Metalloproteinases and collagen‐stimulating factors play an important role in …

In vitro and pilot in vivo evaluation of a bioactive coating for stent grafts based on chondroitin sulfate and epidermal growth factor

P Lequoy, H Savoji, B Saoudi… - Journal of Vascular and …, 2016 - Elsevier
Purpose To evaluate the potential of a bioactive coating based on chondroitin sulfate (CS)
and tethered epidermal growth factor (EGF) for improvement of healing around stent grafts …

Donor spontaneous intracerebral hemorrhage is associated with systemic activation of matrix metalloproteinase-2 and matrix metalloproteinase-9 and subsequent …

MH Yamani, RC Starling, DJ Cook, EM Tuzcu, A Abdo… - Circulation, 2003 - Am Heart Assoc
Background—Matrix metalloproteinase (MMP)-2 and MMP-9 have been shown to play a
role in the progression of hemorrhagic stroke. We hypothesized that donor intracerebral …

Plasma and tissue levels of callagen types I and III markers in patients with abdominal aortic aneurysms

V Treska, O Topolcan - International Angiology, 2000 - search.proquest.com
BACKGROUND: To study the levels of the aminoterminal propeptide of type III (PIIINP) and
carboxyterminal propeptide of type I procollagen (PICP) in plasma and in the wall of …