Microporation of tissue for delivery of bioactive agents

JA Eppstein - US Patent 9,579,380, 2017 - Google Patents
Related US Application Data Continuation of application No. 10/284.408, filed on Oct. 31,
2002, now abandoned, which is a continuation of application No. 09/331,124, filed as …

Microporation of tissue for delivery of bioactive agents

JA Eppstein - US Patent 6,527,716, 2003 - Google Patents
(57) ABSTRACT A method of enhancing the permeability of a biological membrane,
including the skin or mucosa of an animal or the outer layer of a 20 plant to a permeant is …

Enhancement of antibody-mediated immune responses

JV Ravetch - US Patent 7,416,726, 2008 - Google Patents
5,814,500 A 9, 1998 Dietz............ 435,172.3 results in binding of the antibody to FcyRIIB with
reduced s. s34, 597 A 11/1998 Tso et al........ 530,387.3 affinity. A variety of transgenic …

Immunostimulation of dendritic cells by cationic liposomes

DP Vangasseri, Z Cui, W Chen, DA Hokey… - Molecular membrane …, 2006 - Taylor & Francis
A nano-aggregate liposome-polycation-DNA (LPD), composed of a cationic lipid, protamine
and plasmid DNA was found to effectively deliver a human papillomavirus (HPV)-E7 epitope …

Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA

YX Li, M Farrell, M Kirby - US Patent App. 10/038,984, 2002 - Google Patents
US20020114784A1 - Composition and method for in vivo and in vitro attenuation of gene
expression using double stranded RNA - Google Patents US20020114784A1 …

Oligoribonucleotides and ribonucleases for cleaving RNA

ST Crooke - US Patent 7,695,902, 2010 - Google Patents
Oligomeric compounds including oligoribonucleotides and oligoribonucleosides are
provided that have subsequences of 2'-pentoribofuranosyl nucleosides that activate …

Lipid-mediated polynucleotide administration to deliver a biologically active peptide and to induce a cellular immune response

PL Felgner, JA Wolff, GH Rhodes, RW Malone… - US Patent …, 2007 - Google Patents
(60) Continuation of application No. 08/486,533, filed on WO WO 91, 07487 5, 1991 Jun. 7,
1995, now Pat. No. 6,867,195, which is a WO WO 91/16024 10, 1991 continuation of …

Beverage filter cartridge holder

NG Lazaris, RH Beaulieu - US Patent 6,644,173, 2003 - Google Patents
A beverage is brewed by infusing heated liquid with a dry beverage medium contained in a
first chamber of a disposable cartridge. The cartridge is internally subdivided by a …

Compositions comprising alternating 2′-modified nucleosides for use in gene modulation

C Allerson, B Bhat, AB Eldrup, M Manoharan… - US Patent …, 2013 - Google Patents
2004-05-18 Assigned to ISIS PHARMACEUTICALS, INC. reassignment ISIS
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Positionally modified siRNA constructs

B Bhat, EE Swayze, TP Prakash, C Allerson… - US Patent …, 2013 - Google Patents
The present invention provides oligomeric compounds hav ing su? icient complementarity to
hybridize to a nucleic acid target and methods for their use in modulating gene expres sion …