Chitosan hydrogels for sustained drug delivery

S Peers, A Montembault, C Ladavière - Journal of Controlled Release, 2020 - Elsevier
Sustainable and controlled delivery of drugs is at the centre of a huge amount of undertaken
researches. The ability of hydrogels, high water content materials, to achieve a local and …

Long-term delivery of protein therapeutics

R Vaishya, V Khurana, S Patel… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Proteins are effective biotherapeutics with applications in diverse ailments.
Despite being specific and potent, their full clinical potential has not yet been realized. This …

Inflammation targeted chitosan-based hydrogel for controlled release of diclofenac sodium

N Gull, SM Khan, OM Butt, A Islam, A Shah… - International journal of …, 2020 - Elsevier
Inflammation is a key challenge in the treatment of chronic diseases. Spurred by topical
advancement in polymer chemistry and drug delivery, hydrogels that release a drug in …

In vitro study of chitosan-based multi-responsive hydrogels as drug release vehicles: A preclinical study

N Gull, SM Khan, MTZ Butt, S Khalid, M Shafiq… - RSC …, 2019 - pubs.rsc.org
Systematic administration of painkillers and anti-inflammatory drugs is routinely employed to
minimize pain and bodily disorders. Controlled drug delivery has the potential to improve the …

Injectable implants for the sustained release of protein and peptide drugs

P Agarwal, ID Rupenthal - Drug discovery today, 2013 - Elsevier
Protein and peptide macromolecules have emerged as promising therapeutic agents in
recent years. However, their delivery to the target site can be challenging owing to their …

The design of pH-sensitive chitosan-based formulations for gastrointestinal delivery

H Du, M Liu, X Yang, G Zhai - Drug discovery today, 2015 - Elsevier
Highlights•Chitosan is suitable for pH-sensitive gastrointestinal delivery formulation
design.•Chitosan-based formulations in response to different gastrointestinal pH …

Chitosan nanoparticles/cellulose nanocrystals nanocomposites as a carrier system for the controlled release of repaglinide

WS Abo-Elseoud, ML Hassan, MW Sabaa… - International journal of …, 2018 - Elsevier
The aim of the present work was to study the use of cellulose nanocrystals (CNC) and
chitosan nanoparticles (CHNP) for developing controlled-release drug delivery system of the …

Hybrid cross‐linked hydrogels as a technology platform for in vitro release of cephradine

N Gull, SM Khan, MTZ Butt, S Zia… - Polymers for …, 2019 - Wiley Online Library
Hydrogel‐based drug delivery systems can leverage therapeutically favorable upshots of
drug release and found clinical uses. Hydrogels offer temporal and spatial control over the …

[PDF][PDF] Interpenetrating polymer network hydrogels of chitosan: applications in controlling drug release

D Pal, AK Nayak, S Saha - Cellulose-based superabsorbent …, 2018 - researchgate.net
Chitosan is a natural polysaccharide obtained by alkaline deacetylation of chitin. It is
cationic in ionic nature. Because of its biocompatibility and biodegradability, chitosan is …

Chitosan microparticles for the controlled delivery of fluoride

GM Keegan, JD Smart, MJ Ingram, LM Barnes… - Journal of dentistry, 2012 - Elsevier
OBJECTIVES: To manufacture and characterise chitosan/fluoride microparticles prepared by
spray drying and assess their utility as controlled release vehicles for fluoride. METHODS …