Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic
kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …

IL-10, IL-6, and TNF-α: Central factors in the altered cytokine network of uremia—The good,
the bad, and the ugly. It has been increasingly apparent that wasting and cardiovascular …

This review focuses on the association between vascular calcification and arterial stiffness,
highlighting the important genetic factors, systemic and local microenvironmental signals …

The final step of biomineralization is a chemical precipitation reaction that occurs
spontaneously in supersaturated or metastable salt solutions. Genetic programs direct …

Premature cardiovascular disease (CVD), including stroke, peripheral vascular disease,
sudden death, coronary artery disease, and congestive heart failure, is a notorious problem …

The first reports connecting uremic inflammation with a wasted and atherogenic phenotype
and poor outcome initiated in the late 1990s. Since then, about 3500 publications appear on …

Background: Serum albumin (S-Alb), C-reactive protein (CRP), and interleukin 6 (IL-6)
predict malnutrition, atherosclerotic cardiovascular disease (CVD), and mortality in patients …

Context Fetuin-A is a hepatic secretory protein that binds the insulin receptor and inhibits
insulin action in vitro. In prior cross-sectional studies in humans, higher fetuin-A levels were …

Vascular calcification predicts an increased risk for cardiovascular events/mortality in
atherosclerosis, diabetes, and ESRD. Serum concentrations of α 2-Heremens-Schmid …