IL-1β and the intestinal epithelial tight junction barrier

LW Kaminsky, R Al-Sadi, TY Ma - Frontiers in immunology, 2021 - frontiersin.org
The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

The intestinal barrier and current techniques for the assessment of gut permeability

I Schoultz, ÅV Keita - Cells, 2020 - mdpi.com
The intestinal barrier is essential in human health and constitutes the interface between the
outside and the internal milieu of the body. A functional intestinal barrier allows absorption of …

Disorders of the enteric nervous system—a holistic view

B Niesler, S Kuerten, IE Demir… - … reviews Gastroenterology & …, 2021 - nature.com
The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

The roles of Peyer's patches and microfold cells in the gut immune system: relevance to autoimmune diseases

N Kobayashi, D Takahashi, S Takano… - Frontiers in …, 2019 - frontiersin.org
Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid
tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport …

High-throughput screen identifies host and microbiota regulators of intestinal barrier function

I Grosheva, D Zheng, M Levy, O Polansky… - Gastroenterology, 2020 - Elsevier
Background & Aims The intestinal barrier protects intestinal cells from microbes and
antigens in the lumen—breaches can alter the composition of the intestinal microbiota, the …

A review of heat stress in chickens. Part I: Insights into physiology and gut health

G Brugaletta, JR Teyssier, SJ Rochell, S Dridi… - Frontiers in …, 2022 - frontiersin.org
Heat stress (HS) compromises the yield and quality of poultry products and endangers the
sustainability of the poultry industry. Despite being homeothermic, chickens, especially fast …

Fecal microbiota transplantation prevents intestinal injury, upregulation of toll-like receptors, and 5-fluorouracil/oxaliplatin-induced toxicity in colorectal cancer

CW Chang, HC Lee, LH Li, JS Chiang Chiau… - International journal of …, 2020 - mdpi.com
FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin), a 5-fluorouracil (5-FU)-based
chemotherapy regimen, is one of most common therapeutic regimens for colorectal cancer …

Intestinal microbiome and fitness in kidney disease

B Meijers, P Evenepoel, HJ Anders - Nature reviews nephrology, 2019 - nature.com
Environmental changes can induce diversity shifts within ecosystems that affect interactions
between species. Similarly, the development of kidney disease induces shifts within the …

The integral role of tight junction proteins in the repair of injured intestinal epithelium

ZM Slifer, AT Blikslager - International journal of molecular sciences, 2020 - mdpi.com
The intestinal epithelial monolayer forms a transcellular and paracellular barrier that
separates luminal contents from the interstitium. The paracellular barrier consists of a highly …

The immunomodulatory effect of the gut microbiota in kidney disease

M Chi, K Ma, J Wang, Z Ding, Y Li, S Zhu… - Journal of …, 2021 - Wiley Online Library
The human gut microbiota is a complex cluster composed of 100 trillion microorganisms,
which holds a symbiotic relationship with the host under normal circumstances. Intestinal …