Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Obesity leads to an inflammatory condition that is directly involved in the etiology of
cardiovascular diseases, type 2 diabetes mellitus, and certain types of cancer. The classic …

Toll-like receptors (TLRs) are fundamental sensor molecules of the host innate immune
system, which detect conserved molecular signatures of a wide range of microbial …

Toll-like receptors (TLRs) activation enables host to recognize a large number of pathogen-
associated molecule patterns (PAMPs), ignite immune cells to discriminate between self and …

Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …

Immune-checkpoint protein V-domain immunoglobulin suppressor of T-cell activation
(VISTA) controls antitumor immunity and is a valuable target for cancer immunotherapy. This …

The inflammasome NLRP3 is activated by pathogen associated molecular patterns (PAMPs)
during infection, including RNA and proteins from influenza A virus (IAV). However, chronic …

Abstract Toll-like receptor (TLR) 4 is an important polysaccharide receptor; however, the
relationships between the structures and biological activities of TLR4 and polysaccharides …

The endosomal Toll-like receptors (TLRs) TLR3, TLR7, TLR8 and TLR9 are important in
sensing foreign nucleic acids encountered by phagocytes. Because TLR8 was initially …

Acute obstruction of a coronary artery causes myocardial ischaemia and if prolonged, may
result in an ST-segment elevation myocardial infarction (STEMI). First-line treatment involves …