[HTML][HTML] Therapeutic implications of tumor microenvironment in lung cancer: focus on immune checkpoint blockade

C Genova, C Dellepiane, P Carrega… - Frontiers in …, 2022 - frontiersin.org
In the last decade, the treatment of non-small cell lung cancer (NSCLC) has been
revolutionized by the introduction of immune checkpoint inhibitors (ICI) directed against …

[HTML][HTML] IL-17 cytokines and chronic lung diseases

F Ritzmann, LP Lunding, R Bals, M Wegmann… - Cells, 2022 - mdpi.com
IL-17 cytokines are expressed by numerous cells (eg, gamma delta (γδ) T, innate lymphoid
(ILC), Th17, epithelial cells). They contribute to the elimination of bacteria through the …

[HTML][HTML] Reprogramming of Treg cells in the inflammatory microenvironment during immunotherapy: a literature review

X Wu, Z Zhou, Q Cao, Y Chen, J Gong… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Treg), as members of CD4+ T cells, have garnered extensive attention in
the research of tumor progression. Treg cells have the function of inhibiting the immune …

[HTML][HTML] Radiomics for characterization of the glioma immune microenvironment

N Khalili, AF Kazerooni, A Familiar, D Haldar… - NPJ precision …, 2023 - nature.com
Increasing evidence suggests that besides mutational and molecular alterations, the
immune component of the tumor microenvironment also substantially impacts tumor …

[HTML][HTML] KRAS as a modulator of the inflammatory tumor microenvironment: therapeutic implications

F Pereira, A Ferreira, CA Reis, MJ Sousa, MJ Oliveira… - Cells, 2022 - mdpi.com
KRAS mutations are one of the most frequent oncogenic mutations of all human cancers,
being more prevalent in pancreatic, colorectal, and lung cancers. Intensive efforts have been …

[HTML][HTML] Deep learning for lung cancer diagnosis, prognosis and prediction using histological and cytological images: a systematic review

A Davri, E Birbas, T Kanavos, G Ntritsos, N Giannakeas… - Cancers, 2023 - mdpi.com
Simple Summary Lung cancer is one of the most common and deadly malignancies
worldwide. Microscopic examination of histological and cytological lung specimens can be a …

[HTML][HTML] Targeting inflammation in non-small cell lung cancer through drug repurposing

T Rajasegaran, CW How, A Saud, A Ali, JCW Lim - Pharmaceuticals, 2023 - mdpi.com
Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …

[HTML][HTML] Cancer stem cells (CSCs), circulating tumor cells (CTCs) and their interplay with cancer associated fibroblasts (CAFs): a new world of targets and treatments

B Aramini, V Masciale, C Arienti, M Dominici, F Stella… - Cancers, 2022 - mdpi.com
Simple Summary The world of small molecules in solid tumors as cancer stem cells (CSCs),
circulating tumor cells (CTCs) and cancer-associated fibroblasts (CAFs) continues to be …

Research progress and value of albumin-related inflammatory markers in the prognosis of non-small cell lung cancer: A review of clinical evidence

C Zhang, M Gao, X Jiang, X Pan, X Zhang, Y Li… - Annals of …, 2023 - Taylor & Francis
Inflammatory markers have a wide range of predictive values in the prognosis of non-small
lung cancer (NSCLC). Poor nutritional status usually means a poor prognosis in patients …

Prognostic value of inflammatory response biomarkers using peripheral blood and [18F]-FDG PET/CT in advanced NSCLC patients treated with first-line chemo-or …

RD Seban, JB Assié, E Giroux-Leprieur, MA Massiani… - Lung Cancer, 2021 - Elsevier
Objectives We aimed to compare the prognostic value of inflammatory biomarkers extracted
from pretreatment peripheral blood and [18F]-FDG PET for estimating outcomes in non-small …