Coronary microvascular dysfunction

F Vancheri, G Longo, S Vancheri, M Henein - Journal of Clinical …, 2020 - mdpi.com
Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options: JACC State-of-the-Art Review

VR Taqueti, MF Di Carli - Journal of the American College of Cardiology, 2018 - jacc.org
Coronary microvascular disease (CMD) refers to the subset of disorders affecting the
structure and function of the coronary microcirculation, is prevalent in patients across a …

The human microcirculation: regulation of flow and beyond

DD Gutterman, DS Chabowski, AO Kadlec… - Circulation …, 2016 - Am Heart Assoc
The microcirculation is responsible for orchestrating adjustments in vascular tone to match
local tissue perfusion with oxygen demand. Beyond this metabolic dilation, the …

Coronary microvascular dysfunction

PG Camici, F Crea - New England Journal of Medicine, 2007 - Mass Medical Soc
This review discusses the pathogenesis and management of coronary microvascular
dysfunction. Factors to consider in clinical management are the cause of the dysfunction and …

Retinal arteriolar narrowing and risk of coronary heart disease in men and women: the Atherosclerosis Risk in Communities Study

TY Wong, R Klein, AR Sharrett, BB Duncan, DJ Couper… - Jama, 2002 - jamanetwork.com
ContextMicrovascular processes have been hypothesized to play a greater role in the
development of coronary heart disease (CHD) in women than in men; however, prospective …

Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality

TY Wong, R Klein, BEK Klein, JM Tielsch… - Survey of …, 2001 - Elsevier
Retinal microvascular abnormalities, such as generalized and focal arteriolar narrowing,
arteriovenous nicking and retinopathy, reflect cumulative vascular damage from …

From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease

AH Gradman, F Alfayoumi - Progress in cardiovascular diseases, 2006 - Elsevier
Other than age, left ventricular hypertrophy (LVH) is the most potent predictor of adverse
cardiovascular outcomes in the hypertensive population, and is an independent risk factor …

Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan

EL Schiffrin, JB Park, HD Intengan, RM Touyz - Circulation, 2000 - Am Heart Assoc
Background—Structural and functional alterations of the vasculature may contribute to
complications of hypertension. Because angiotensin II may be pivotal in some of these …

Association of isolated coronary microvascular dysfunction with mortality and major adverse cardiac events: a systematic review and meta‐analysis of aggregate data

MA Gdowski, VL Murthy, M Doering… - Journal of the …, 2020 - Am Heart Assoc
Background The impact of coronary microvascular dysfunction (CMD), as diagnosed by
reduced coronary flow reserve, on the outcomes of patients with symptoms of myocardial …

Abnormalities of retinal microvascular structure and risk of mortality from ischemic heart disease and stroke

N Witt, TY Wong, AD Hughes, N Chaturvedi… - …, 2006 - Am Heart Assoc
Abnormalities of the retinal microcirculation are found in hypertension and diabetes and
predict cardiovascular mortality. This study examined the relationship between …