Development of prefrontal cortex
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …
Striatal circuits for reward learning and decision-making
The striatum is essential for learning which actions lead to reward and for implementing
those actions. Decades of experimental and theoretical work have led to several influential …
those actions. Decades of experimental and theoretical work have led to several influential …
Spontaneous behaviour is structured by reinforcement without explicit reward
Spontaneous animal behaviour is built from action modules that are concatenated by the
brain into sequences,. However, the neural mechanisms that guide the composition of …
brain into sequences,. However, the neural mechanisms that guide the composition of …
Mesolimbic dopamine release conveys causal associations
Learning to predict rewards based on environmental cues is essential for survival. It is
believed that animals learn to predict rewards by updating predictions whenever the …
believed that animals learn to predict rewards by updating predictions whenever the …
Geometry of abstract learned knowledge in the hippocampus
Hippocampal neurons encode physical variables,,,,,–such as space or auditory frequency in
cognitive maps. In addition, functional magnetic resonance imaging studies in humans have …
cognitive maps. In addition, functional magnetic resonance imaging studies in humans have …
A solution to the learning dilemma for recurrent networks of spiking neurons
Recurrently connected networks of spiking neurons underlie the astounding information
processing capabilities of the brain. Yet in spite of extensive research, how they can learn …
processing capabilities of the brain. Yet in spite of extensive research, how they can learn …
[HTML][HTML] Dopamine release in the nucleus accumbens core signals perceived saliency
A large body of work has aimed to define the precise information encoded by dopaminergic
projections innervating the nucleus accumbens (NAc). Prevailing models are based on …
projections innervating the nucleus accumbens (NAc). Prevailing models are based on …
Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control
L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …
including motor control, modulation of affective and emotional states, reward mechanisms …
Unique functional responses differentially map onto genetic subtypes of dopamine neurons
Dopamine neurons are characterized by their response to unexpected rewards, but they
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …
VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error
C Solié, B Girard, B Righetti, M Tapparel… - Nature …, 2022 - nature.com
Social interactions are motivated behaviors that, in many species, facilitate learning.
However, how the brain encodes the reinforcing properties of social interactions remains …
However, how the brain encodes the reinforcing properties of social interactions remains …