Development of prefrontal cortex

SM Kolk, P Rakic - Neuropsychopharmacology, 2022 - nature.com
During evolution, the cerebral cortex advances by increasing in surface and the introduction
of new cytoarchitectonic areas among which the prefrontal cortex (PFC) is considered to be …

Striatal circuits for reward learning and decision-making

J Cox, IB Witten - Nature Reviews Neuroscience, 2019 - nature.com
The striatum is essential for learning which actions lead to reward and for implementing
those actions. Decades of experimental and theoretical work have led to several influential …

Spontaneous behaviour is structured by reinforcement without explicit reward

JE Markowitz, WF Gillis, M Jay, J Wood, RW Harris… - Nature, 2023 - nature.com
Spontaneous animal behaviour is built from action modules that are concatenated by the
brain into sequences,. However, the neural mechanisms that guide the composition of …

Mesolimbic dopamine release conveys causal associations

H Jeong, A Taylor, JR Floeder, M Lohmann, S Mihalas… - Science, 2022 - science.org
Learning to predict rewards based on environmental cues is essential for survival. It is
believed that animals learn to predict rewards by updating predictions whenever the …

Geometry of abstract learned knowledge in the hippocampus

EH Nieh, M Schottdorf, NW Freeman, RJ Low… - Nature, 2021 - nature.com
Hippocampal neurons encode physical variables,,,,,–such as space or auditory frequency in
cognitive maps. In addition, functional magnetic resonance imaging studies in humans have …

A solution to the learning dilemma for recurrent networks of spiking neurons

G Bellec, F Scherr, A Subramoney, E Hajek… - Nature …, 2020 - nature.com
Recurrently connected networks of spiking neurons underlie the astounding information
processing capabilities of the brain. Yet in spite of extensive research, how they can learn …

[HTML][HTML] Dopamine release in the nucleus accumbens core signals perceived saliency

MG Kutlu, JE Zachry, PR Melugin, SA Cajigas… - Current Biology, 2021 - cell.com
A large body of work has aimed to define the precise information encoded by dopaminergic
projections innervating the nucleus accumbens (NAc). Prevailing models are based on …

Dopamine: the neuromodulator of long-term synaptic plasticity, reward and movement control

L Speranza, U Di Porzio, D Viggiano, A de Donato… - Cells, 2021 - mdpi.com
Dopamine (DA) is a key neurotransmitter involved in multiple physiological functions
including motor control, modulation of affective and emotional states, reward mechanisms …

Unique functional responses differentially map onto genetic subtypes of dopamine neurons

M Azcorra, Z Gaertner, C Davidson, Q He, H Kim… - Nature …, 2023 - nature.com
Dopamine neurons are characterized by their response to unexpected rewards, but they
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …

VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error

C Solié, B Girard, B Righetti, M Tapparel… - Nature …, 2022 - nature.com
Social interactions are motivated behaviors that, in many species, facilitate learning.
However, how the brain encodes the reinforcing properties of social interactions remains …