The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Adiponectin (ApN) is a hormone abundantly secreted by adipocytes and it is known to be
tightly linked to the metabolic syndrome. It promotes insulin-sensitizing, fat-burning, and anti …

Abstract Introduction Documented Duchenne Muscular Dystrophy (DMD) biomarkers are
confined to Caucasians and are poor indicators of cognitive difficulties and …

Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by absence of the
protein dystrophin, which acts as a structural link between the basal lamina and contractile …

The muscle stem cells niche is essential in neuromuscular disorders. Muscle injury and
myofiber death are the main triggers of muscle regeneration via satellite cell activation …

New medicines are urgently required to treat the fatal neuromuscular disease Duchenne
muscular dystrophy (DMD). Dimethyl fumarate (DMF) is a potent immunomodulatory small …

Glucocorticoid steroids are widely used as immunomodulatory agents in acute and chronic
conditions. Glucocorticoid steroids such as prednisone and deflazacort are recommended …

Duchenne muscular dystrophy (DMD) is one of the most devastating myopathies, where
severe inflammation exacerbates disease progression. Previously, we demonstrated that …

Duchenne muscular dystrophy is an inherited disorder of early childhood that affects
multiple systems in the body. Besides late-onset cardio-respiratory syndrome and various …

Background Blood accessible biomarkers to assess disease activity and their response to
therapies in Juvenile Dermatomyositis (JDM) are urgently needed. This pilot study aims to …