Addiction is commonly identified with habitual nonmedical self-administration of drugs. It is
usually defined by characteristics of intoxication or by characteristics of withdrawal …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Studies addressing behavioral functions of dopamine (DA) in the nucleus accumbens septi
(NAS) are reviewed. A role of NAS DA in reward has long been suggested. However, some …

This article reviews current research and cross-disciplinary perspectives on the
neuroscience of food reward in animals and humans, examines the scientific hypothesis of …

The objective of this non-systematic review of the literature is to highlight some of the neural
systems and pathways that are affected by the various intake-promoting aspects of the …

Seven healthy subjects underwent two [11C] raclopride positron emission tomography (PET)
scans, one following a 16-h fast and the other after consumption of a favorite meal (following …

The motivation to seek out and consume rewards has evolutionarily been driven by the urge
to fulfill physiological needs. However in a modern society dominated more by plenty than …

The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …