The biochemical indicators of tumor microenvironment (TME) that are different from normal
tissues provide the possibility for constructing intelligent drug delivery systems (DDSs) …

Ferroptosis, a completely new form of regulated cell death, is mainly caused by an
imbalance between oxidative damage and reductive protection and has shown great anti …

The synergy of living microbial and small-molecular therapeutics has been widely explored
for treating a variety of diseases, while current combination strategies often suffer from low …

Polymeric micellar drug carriers have emerged as effective tools to enhance the solubility
and bioavailability of hydrophobic drugs. These micelles possess a nano size structure that …

Bacterial infection is one of the leading causes of death globally, although modern medicine
has made considerable strides in the past century. As traditional antibiotics are suffering …

Purpose Oxidative stress, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-
κB) and adenosine signaling are factors associated with psoriatic inflammation. Topical …

Brain diseases, including neurodegenerative diseases, acute ischemic stroke and brain
tumors, have become a major health problem and a huge burden on society with high …

Primary brain and central nervous system (CNS) tumors are a diverse group of neoplasms
that occur within the brain and spinal cord. Although significant advances in our …

The cellular milieu in which malignant growths or cancer stem cells reside is known as the
tumour microenvironment (TME). It is the consequence of the interactivity amongst malignant …

Oxidative stress injury and mitochondrial dysfunction are major obstacles to neurological
functional recovery after ischemic stroke. The development of new approaches to …