Background Neurodegenerative diseases are a common group of neurological disorders
characterized by progressive loss of neuronal structure and function leading to cognitive …

Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis
(PSC), and IgG4-related sclerosing cholangitis (IgG4-SC) are the four main forms of …

The gasdermin (GSDM) protein family plays a pivotal role in pyroptosis, a process critical to
the body's immune response, particularly in combatting bacterial infections, impeding tumor …

Listeria monocytogenes (Lm), a foodborne bacterium, can infect people and has a high
fatality rate in immunocompromised individuals. Listeriolysin O (LLO), the primary virulence …

In the recent past, the concept of immunity has been extended to eukaryotic and prokaryotic
microorganisms, like fungi and bacteria. The latest findings have drawn remarkable …

Programmed cell death pathways play important roles in a wide variety of physiological
processes. Although it has similarities with apoptosis pyroptosis is a different type of …

Nickel (Ni) is considered a toxic metal, and excessive exposure can cause kidney damage.
This study was designed to explore whether nickel chloride (NiCl2) can induce cell …

In the process of sepsis, excessive occurrence of pyroptosis, a form of programmed cell
death acting as a defense mechanism against pathogens, can disrupt immune responses …

As the outermost layer of the human body, the skin suffers from various external factors
especially light damage, among which ultraviolet B (UVB) irradiation is common and …

Cell membrane is crucial for the cellular activities, and any disruption to it may affect the
cells. It is demonstrated that cell membrane perforation is associated with some biological …